, Volume 54, Issue 6, pp 801–840 | Cite as

The Role of Plant-Derived Drugs and Herbal Medicines in Healthcare

  • Peter A. G. M. De SmetEmail author
Review Article


Many of our present medicines are derived directly or indirectly from higher plants. While several classic plant drugs have lost much ground to synthetic competitors, others have gained a new investigational or therapeutical status in recent years. In addition, a number of novel plant-derived substances have entered into Western drug markets. Clinical plant-based research has made particularly rewarding progress in the important fields of anticancer (e.g. taxoids and camptothecins) and antimalarial (e.g. artemisinin compounds) therapies. In addition to purified plant-derived drugs, there is an enormous market for crude herbal medicines.

Natural product research can often be guided by ethnopharmacological knowledge, and it can make substantial contributions to drug innovation by providing novel chemical structures and/or mechanisms of action. In the end, however, both plant-derived drugs and crude herbal medicines have to take the same pharmaco-economic hurdle that has become important for new synthetic pharmaceuticals.


Paclitaxel Malaria Atopic Eczema Artemisinin Familial Mediterranean Fever 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Adis International Limited 1997

Authors and Affiliations

  1. 1.Pharmaceutical Care UnitScientific Institute Dutch PharmacistsThe HagueThe Netherlands

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