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Drugs

, Volume 43, Supplement 2, pp 40–47 | Cite as

The Safety of Antidepressants

  • F. de Jonghe
  • J. A. Swinkels
Article

Summary

In this article, a distinction is proposed between safe and less safe antidepressants. The safety of 18 antidepressants is discussed in relation to 3 principal issues: the safety of the drug in the event of an overdose; the seriousness of its side effects; and the existence of dangerous interactions. On the basis of present information, it can be said with reasonable confidence that fluoxetine, fluvoxamine and paroxetine are safe antidepressants, and with some reservation (mainly because of hypnosedation) the same can be said of mianserin and trazodone.

Keywords

Fluoxetine Paroxetine Imipramine Amitriptyline Orthostatic Hypotension 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Adis International Limited 1992

Authors and Affiliations

  • F. de Jonghe
    • 1
  • J. A. Swinkels
    • 2
  1. 1.Department of PsychiatryUniversity of Amsterdam, Academic Medical Centre, and Social Psychiatric Services CentreAmsterdamThe Netherlands
  2. 2.Outpatient Psychiatry ClinicAcademic Medical CentreAmsterdamThe Netherlands

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