Drugs

, Volume 40, Issue 4, pp 531–542 | Cite as

Current Concepts in the Treatment of Immune Thrombocytopenia

  • Theodore E. Warkentin
  • John G. Kelton
Practical Therapeutics

Summary

Platelet destruction by antibodies is a common cause, of thrombocytopenia. In this review, various treatments for immune thrombocytopenia are discussed, with emphasis on corticosteroids, splenectomy, danazol, high-dose immunoglobulin G, anti-Rhesus globulin, colchicine and cytotoxic, immuftosuppressive agents such as cyclophosphamide and azathioprine. An approach to the treatment of adult idiopathic thrombocytopenic purpura (ITP) is reviewed in detail and the treatments for several other immune thrombocytopenic disorders are summarised.

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Copyright information

© Adis International Limited 1990

Authors and Affiliations

  • Theodore E. Warkentin
    • 1
    • 2
    • 3
  • John G. Kelton
    • 1
    • 2
    • 3
  1. 1.Department of PathologyMcMaster University Medical CentreHamiltonCanada
  2. 2.McMaster University Medical CentreHamiltonCanada
  3. 3.Canadian Red Cross Blood Transfusion ServiceHamilton CentreHamiltonOntarioCanada

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