Skip to main content
Log in

Glibenclamide, a New Sulphonylurea: Whither Oral Hypoglycaemic Agents?

  • Guest Editorial
  • Published:
Drugs Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Ruiz, CL.; Silva, L.L., and Libenson, L.: Contribución al estudio sobre la composición química de la insulina. Estudio de algunos cuerpos sintéticos sulfurados con acción hipoglucemiante. Revista de la Sociedad argentina de biología 6: 134 (1930).

    CAS  Google Scholar 

  2. Savagnone, L.: Sulfamidi e recambio idrocarbonato influenza della somministrazione di sulfamidi sul tasso glicemico in condizioni normali e patológiche. Settimana médica 29: 1005(1941).

    Google Scholar 

  3. Loubatières, A.: Analyse du mécanisme de l’action hypoglycémiante du p-amino-benzène sulfamido thiodiazol (2254 R.P.). Comptes rendus des séances de la Société de biologie et de ses filiales 138: 766 (1944).

    Google Scholar 

  4. Janbon, M.; Chaptal, J.; Vedel, A. et Schaap, J.: Accidents hypoglycémiques graves par un sulfamido-thiodiazol (le V.K. 57 ou 2254 R.P.). Montpellier médical 21s-22: 441 (1942).

    Google Scholar 

  5. Franke, H. und Fuchs, J.: Ein neues antidiabetisches Prinzip. Deutsche medizinische Wochenschrift 80: 1449 (1955).

    Article  PubMed  CAS  Google Scholar 

  6. Creutzfeldt, W. and Söling, H.-D.: Oral treatment of Diabetes: A Clinical and Experimental Review, p. 94 (Springer, Berlin 1961).

    Book  Google Scholar 

  7. Aumüller, W.; Bänder, A.; Heerdt, R.; Muth, K.; Pfaff, W.; Schmidt, F.H.; Weber, H. und Weyer, R.: Ein neues hochwirksames orales Antidiabeticum. Arzneimittel-Forschung 16: 1640 (1966).

    PubMed  Google Scholar 

  8. Johnson, B.F.; Bhatia, CK.; Rzeszotarski, W.J., and Wolff, F.W.: Preliminary clinical evaluation of gli-benclamide in treatment of diabetes mellitus. Diabetes 19: 579 (1970).

    PubMed  CAS  Google Scholar 

  9. Raptis, S., Rau, R.M.; Schröder, K.E.; Faulhaber, J.D., and Pfeiffer, E.F.: Comparative study of insulin secretion following repeated administration of glucose, tolbutamide and glibenclamide (HB 419) in diabetic and non-diabetic human subjects. Hormone and Metabolic Research 1 (Suppl. 1): 65 (1969).

    Google Scholar 

  10. Levine, R. and Pfeiffer, E.F. (Eds.): HB 419 A new oral antidiabetic drug. (Papers presented at the Tegernsee Conference, in Rottach-Egern, Germany, January 27s-29, 1969.) Hormone and Metabolic Research i (Suppl. 1): 1–92 (1969).

  11. Müller, R.; Bauer, G.; Schröder, R., and Saito, S.: Summary report of clinical investigation of the oral antidiabetic drug HB 419. Hormone and Metabolic Research 1 (Suppl. 1): 88 (1969).

    Google Scholar 

  12. Goldner, M.G. and Prout, T.E.: The University Group Diabetes Program: The effects of hypoglycemic agents on vascular complications in patients with adult onset diabetes. 1. Design and methods (Abstract). Diabetes 19 (Suppl. 1): 387 (1970).

    Google Scholar 

  13. Prout, T.E. and Goldner, M.G.: The University Group Diabetes Program: The effects of hypoglycemic agents on vascular complications in patients with adult onset diabetes. 2. Findings at baseline (Abstract). Diabetes 19 (Suppl. 1): 374 (1970). 3. Course and mortality (Abstract). Ibid. 375.

    Google Scholar 

  14. The University Group Diabetes Program: A study of the effects of hypoglycemic agents on vascular complications in patients with adult-onset diabetes. Diabetes 19 (Suppl. 2): 747–830 (1970).

    Google Scholar 

  15. Balodimos, M. C.; Gleason, R.E.; Bradley, R.F.; Krall, L.P., and Marble, A.: Causes of death after long-term sulfonylurea therapy. Submitted for publication.

  16. Balodimos, M.C.; Rippey, J.H., and Marble, A.: Causes of death and pathological findings in diabetic patients treated with sulfonylurea compounds. Proceedings of the 7th International Congress of Gerontology, Vienna 3 (No. 447): 281 (1966).

  17. Balodimos, M.C.; Marble, A.; Rippey, J.H.; Legg, M.A.; Kuwabara, T., and Gleason, R.E.: Pathological findings after long-term sulfonylurea therapy. Diabetes 17: 503 (1968).

    PubMed  CAS  Google Scholar 

  18. Balodimos, M.C. and Marble, A.: Diabetic angiopathy and sulfonylurea therapy. Minnesota Medicine 57: 1341 (1968).

    Google Scholar 

  19. Keen, H. and Jarrett, R.J.: Discussion of paper by Prout and Goldner (ref. 13). See also Keen, H.; Jarrett, R.J.; Chlouverakis, C, andBoyns, D.R.: The effect of treatment of moderate hyperglycemia on the incidence of arterial disease. Postgraduate Medical Journal 44 (Suppl. Dec): 960 (1968). Also Keen, #.: Minimal diabetes and arterial disease: prevalence and the effect of treatment; in Camerini-Davalos and Cole Early Diabetes, p. 437 (Academic Press, New York 1970).

  20. Paasikivi, J.: Discussion of paper by Prout and Goldner (ref. 13). See also Paasikivi, J: Long-term tolbutamide treatment after myocardial infarction. Acta Medica Scandinavica 757 (Suppl. 507): 1–82 (1970).

    Google Scholar 

  21. Hardin, R.D.: Statement on treatment of diabetes. Diabetes 19: 527 (1970).

    Google Scholar 

  22. American Medical News, November 2, p. 6 (1970).

  23. Marble, A.: Angiopathy in diabetes; an unsolved problem. Diabetes 16: 825 (1967).

    PubMed  CAS  Google Scholar 

  24. American Medical News, November 23, p. 2 (1970).

  25. Editorial: Are antidiabetic drugs dangerous? British Medical Journal 4: 444 (1970).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marble, A. Glibenclamide, a New Sulphonylurea: Whither Oral Hypoglycaemic Agents?. Drugs 1, 109–115 (1971). https://doi.org/10.2165/00003495-197101020-00001

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2165/00003495-197101020-00001

Navigation