Drug Safety

, Volume 18, Issue 2, pp 135–142

Treating Breast Cancer During Pregnancy

What Can be Taken Safely?
  • Marc Espié
  • Caroline Cuvier
Review Article Drug Safety Concept

DOI: 10.2165/00002018-199818020-00005

Cite this article as:
Espié, M. & Cuvier, C. Drug-Safety (1998) 18: 135. doi:10.2165/00002018-199818020-00005


The occurrence of breast cancer during pregnancy is a rare clinical situation. However, if it is diagnosed, a multidisciplinary approach involving an obstetrician, a medical oncologist and a surgeon is needed. In this situation, breast cancer should be treated according to the same principles applied in nonpregnant patients. Termination of pregnancy does not improve survival. Decisions regarding abortion should be based on the desires of the patient and on therapeutic necessities.

If required, surgery is always possible, but radiation therapy should be avoided because of the risk of fetal toxicity. Antineoplastic drug therapy, if indicated, is possible after the first trimester.

Copyright information

© Adis International Limited 1998

Authors and Affiliations

  • Marc Espié
    • 1
  • Caroline Cuvier
    • 1
  1. 1.Centre des Maladies du Scin, Oncologie Médicale Pr M. MartyHôpital St LouisParisFrance
  2. 2.Centre des Maladies du Scin, Oncologie Médicale Service du Pr MartyHôpital St LouisParis cedex 10France

Personalised recommendations