In this issue of Molecular Medicine, Irvine et al. (1) expound upon the application of molecular biology in clinical medicine and the enabling of targeted interactions at a molecular level over the past decade. In neuroscience, this entails specific interactions with neurons and glial cells. Examples of current research include technologies designed to allow better interaction with neural cells, advanced molecular imaging, materials and hybrid molecules used in neural regeneration, pharmacological neuroprotection, and targeted delivery of drugs and small molecules across the blood-brain barrier. Currently, the most popular molecular medicine topic in neuroscience is the use of molecular imaging techniques. Research on cellular changes has shed invaluable new light on the pathophysiology and biochemistry of neurological diseases. Clinical and experimental use of molecular imaging methods is expanding and now allows quantitative assessment. Molecular imaging may therefore...
- 6.Schaller B. (2005) Positron emission tomography in neuroscience. An integrative part of clinical diagnostic methods and experimental research [in German]. Radiologe 45:186, 188–96.Google Scholar
- 11.Young H, et al. (1999) Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations. European Organization for Research and Treatment of Cancer (EORTC) PET Study Group. Eur. J. Cancer 35:1773–82.CrossRefGoogle Scholar