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High-Performance Separation by Capillary Tube Isotachophoresis Utilizing Complex-Forming Equilibria

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Abstract

Developments in the migrating systems to improve the resolution and sensitivity of capillary tube isotachophoresis (ITP) are described. They are related to the use of complex-forming equilibria in the migrating column and nonaqueous solvents as the migrating medium. The considered sources of ligand for the complex-forming equilibria are (a) the counter ion in the leading electrolyte, (b) the neutral ligands added into the leading electrolyte and (c) the terminating ions. Actual separations performed by these systems are shown and their features and advantages are discussed. Migrating systems consisting of nonaqueous solvents such as dimethylformamide and acetonitrile enable the migration of analyte species which can not be realized in an aqueous medium to improve the selectively and sensitivity. Combining ITP with solvent extraction provides useful analytical techniques.

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References

  1. F. M. Everaerts, J. L. Beckers and Th. P. E. M. Verheggen, “Isotachophoresis”, Elsevier, Amsterdam, Oxford and New York, 1976.

    Google Scholar 

  2. P. Boĉek, M. Deml, P. Gebauer and V. Dolnik, “Analytical Isotachophoresis”, VHC, Basel, Cambridge and New York, 1988.

    Google Scholar 

  3. H. Miyazaki and K. Kato, “Isotachophoresis”, Kodansha, Tokyo, 1980.

    Google Scholar 

  4. T. Hirokawa and Y. Kiso, J. Chromatogr., 242, 227 (1982).

    Article  CAS  Google Scholar 

  5. T. Hirokawa and Y. Kiso, J. Chromatogr., 260, 225 (1983).

    Article  CAS  Google Scholar 

  6. T. Hirokawa, N. Aoki and Y. Kiso, J. Chromatogr., 312, 11 (1984).

    Article  CAS  Google Scholar 

  7. H. Yoshida and Y. Hirama, J. Chromatogr., 298, 243 (1984).

    Article  CAS  Google Scholar 

  8. I. Nukatsuka, M. Taga and H. Yoshida, J. Chromatogr., 205, 95 (1981).

    Article  CAS  Google Scholar 

  9. F. M. Everaerts, Th. P. E. M. Verheggen, J. C. Reijenga, G. V. A. Aben, P. Gebauer and P. Bocek, J. Chromatogr., 320, 263 (1985).

    Article  CAS  PubMed  Google Scholar 

  10. I. Nukatsuka, M. Taga and H. Yoshida, Bull. Chem. Soc. Jpn., 54, 2629 (1981).

    Article  CAS  Google Scholar 

  11. I. Nukatsuka and H. Yoshida, J. Chromatogr., 237, 506 (1982).

    Article  CAS  Google Scholar 

  12. M. Kan, F. Komatsu, S. Tanaka, H. Yoshida and M. Taga, J. Chromatogr., 478, 238 (1989).

    Article  CAS  Google Scholar 

  13. M. Taga, M. Kan, F. Komatsu, S. Tanaka and H. Yoshida, Anal. Sci., 5, 219 (1989).

    Article  CAS  Google Scholar 

  14. F. S. Stover and J. H. Wagenknecht, Anal Chim. Acta, 135, 347 (1982).

    Article  CAS  Google Scholar 

  15. D. Kaniansky and F. M. Everaerts, J. Chromatogr., 148, 441 (1978).

    Article  CAS  Google Scholar 

  16. I. Motooka, K. Nakazaki, H. Nariai and M. Tsuhako, J. Chromatogr., 367, 271 (1986).

    Article  CAS  Google Scholar 

  17. I. Motooka, H. Nariai, K. Nakazaki and M. Tsuhako, J. Chromatogr., 295, 533 (1984).

    Article  CAS  Google Scholar 

  18. P. Bocek, I. Miedziak, M, Demi and J. Janák, J. Chromatogr., 137, 83 (1977).

    Article  CAS  Google Scholar 

  19. I. Zelensky, V. Zelenská D. Kaniansky, P. Havaši and V. Lednárová, J. Chromatogr., 294, 317 (1984).

    Article  CAS  Google Scholar 

  20. J. Vacik and I. Muselasovà, J. Chromatogr., 320, 199 (1985).

    Article  CAS  Google Scholar 

  21. H. Yoshida, I. Nukatsuka and M. Taga, Bunseki Kagaku, 28, 382 (1979).

    Article  CAS  Google Scholar 

  22. D. Kaniansky, V. Madajová, I. Zelensky and S. Stankoviansky, J. Chromatogr., 194, 11 (1980).

    Article  CAS  Google Scholar 

  23. H. Yoshida, M. Hida and M. Taga, J. Chromatogr., 325, 179 (1985).

    Article  CAS  Google Scholar 

  24. H. Yoshida and M. Hida, J. Chromatogr., 351, 388 (1986).

    Article  CAS  Google Scholar 

  25. S. Tanaka, T. Kaneta and H. Yoshida, J. Chromatogr., 472, 303 (1989).

    Article  CAS  Google Scholar 

  26. M. Tazaki, M. Takagi and K. Ueno, Chem. Lett., 1982, 639.

    Google Scholar 

  27. M. Tazaki, T. Hayashita, Y. Fijino and M. Takagi, Bull. Chem. Soc. Jpn., 59, 3459 (1986).

    Article  CAS  Google Scholar 

  28. J. Snopek, I. Jelinek and E. Smolkovà-Keulemansová, J. Chromatogr., 452, 571 (1988).

    Article  CAS  Google Scholar 

  29. S. Tanaka, T. Kaneta, H. Yoshida and H. Ohtaka, J. Chromatogr., 521, 158 (1990).

    Article  CAS  PubMed  Google Scholar 

  30. P. Gebauer, P. Bocek, M. Demi and J. Janak, J. Chromatogr., 199, 81 (1980).

    Article  CAS  Google Scholar 

  31. Y. Hirama and H. Yoshida, J. Chromatogr., 322, 139 (1985).

    Article  CAS  Google Scholar 

  32. Y. Hirama and H. Yoshida, Nippon Kagaku Kaishi, 1986, 943.

    Google Scholar 

  33. S. Tanaka, T. Kaneta and H. Yoshida, J. Chromatgr., 447, 383 (1988).

    Article  CAS  Google Scholar 

  34. S. Tanaka, T. Kaneta and H. Yoshida, Anal Sci., 5, 217 (1989).

    Article  CAS  Google Scholar 

  35. S. Tanaka, T. Kaneta and H. Yoshida, J. Chromatogr., 498, 205 (1990).

    Article  CAS  Google Scholar 

  36. Y. Nakabayashi, Y. Masuda and R. Shinke, Talanta, 36, 639 (1989).

    Article  CAS  PubMed  Google Scholar 

  37. Y. Nakabayashi, Y. Masuda and R. Shinke, Analyst [London], 114, 1109 (1989).

    Article  CAS  Google Scholar 

  38. S. Tanaka, T. Kaneta, K. Nishimura and H. Yoshida, J. Chromatogr., 540, 475 (1991).

    Article  CAS  Google Scholar 

  39. J. C. Reijenga, G. V. A. Aben, Th. P. E. M. Verheggen and F. M. Everaerts, J. Chromatogr., 260, 241 (1983).

    Article  CAS  Google Scholar 

  40. T. Yagi and K. Kojima, Shimadzu Hyoron, 42, 197 (1985).

    CAS  Google Scholar 

  41. J. L. Beckers and F. M. Everaerts, J. Chromatogr., 51, 339 (1970).

    Article  CAS  Google Scholar 

  42. J. L. Beckers, F. M. Everaerts and W. J. M. Houtermans, J. Chromatogr., 76, 277 (1973).

    Article  CAS  PubMed  Google Scholar 

  43. K. Higuchi, T. Nishimura and S. Nakazato, Yukagaku, 28, 890 (1979).

    CAS  Google Scholar 

  44. J. C. Reijenga, H. J. L. A. Slaats and F. M. Everaerts, J. Chromatogr., 267, 85 (1983).

    Article  CAS  PubMed  Google Scholar 

  45. M. Koval, D. Kaniansky, M. Hutta and R. Lacko, J. Chromatogr., 325, 151 (1985).

    Article  CAS  Google Scholar 

  46. K. Fukushi, G. Kondo, K. Hiiro, T. Tanaka, A. Kawahara and S. Wakita, Bunseki Kagaku, 32, 362 (1983).

    Article  CAS  Google Scholar 

  47. M. Koval, D. Kaniansky, L. Mátel and F. Macášek, J. Chromatogr., 243, 144 (1982).

    Article  CAS  Google Scholar 

  48. K. Shimada, M. Ohtsuru, T. Yamaguchi and K. Nigota, J. Food Sci., 48, 665 (1983).

    Article  CAS  Google Scholar 

  49. E. Blasius and U. Wenzel, J. Chromatogr., 49, 527 (1970).

    Article  CAS  Google Scholar 

  50. H. Yoshida and M. Hida, J. Chromatogr., 360, 421 (1986).

    Article  CAS  Google Scholar 

  51. I. Zelensky, D. Kaniansky, P. Havasi, Th. P. E. M. Verheggen and F. M. Everaets, J. Chromatogr., 470, 155 (1989).

    Article  CAS  Google Scholar 

  52. S. Fanali, J. Chromatogr., 474, 441 (1989).

    Article  CAS  Google Scholar 

  53. S. Tanaka, T. Kaneta and H. Yoshida, Anal. Sci., 6, 467 (1990).

    Article  CAS  Google Scholar 

  54. T. Kaneta, S. Tanaka and H. Yoshida, J. Chromatogr., 538, 385 (1991).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, 060, Japan

    Hitoshi Yoshida, Shunitz Tanaka & Takashi Kaneta

  2. Department of Food Science, Hokkaido Institute of Public Health, Kita, Sapporo, 060, Japan

    Yuji Hirama

Authors
  1. Hitoshi Yoshida
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  2. Shunitz Tanaka
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  3. Takashi Kaneta
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  4. Yuji Hirama
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Yoshida, H., Tanaka, S., Kaneta, T. et al. High-Performance Separation by Capillary Tube Isotachophoresis Utilizing Complex-Forming Equilibria. ANAL. SCI. 7, 673–682 (1991). https://doi.org/10.2116/analsci.7.673

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  • DOI: https://doi.org/10.2116/analsci.7.673

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