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Intercalator-Induced Gel-Electrophoretic Retardation of Synthetic Double-Stranded Oligonucleotides and Comigration of Intercalators

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Reference and Notes

  1. C. C. Tsai, S. C. Jain and H. M Sobell, J. Mol Biol., 144, 317 (1977).

    Google Scholar 

  2. E. Loucks, G. Chacohas, R. W. Blakesley, R. D. Wells and H. van de Sande, Nucleic Acids Res., 6, 1869 (1979).

    Article  CAS  Google Scholar 

  3. P. E. Nielsen and W. Zhen, Biochemistry, 27, 67 (1988).

    Article  CAS  Google Scholar 

  4. K. Dohtsu, S. Takenaka, N. Nakashima and M. Takagi, Anal, Sci., 4, 251 (1988).

    Article  Google Scholar 

  5. S. Takenaka, K. Dohtsu, N. Nakashima, and M. Takagi, Ami Sci., 3, 557 (1987).

    CAS  Google Scholar 

  6. In the present case, DNA-intercalator complexes were also able to be stained with ethidium bromide. This is considered to be due to the exchange reaction of ethidium bromide with relevant intercalaltors. When large amounts of inetecalators having higher DNA-binding affinity than ethidium bromide were used, DNA-intercalator complexes was not visualized by ethidium bromide staining.

  7. S. A. Islam, S. Neile, B. M. Gandecha, M. Partrige, L. H, Patterson and J. R. Brown, J. Med, Chem., 28, 857 (1985).

    Article  CAS  Google Scholar 

  8. W. Müller, H. Bunemann and N. Dattagupta, Eur. J. Biochem., 54, 267 (1988).

    Article  Google Scholar 

  9. K. Dohtsu, Y. Katayama and M. Takagi, Chem, Lett., (1986), 1691.

    Google Scholar 

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Authors and Affiliations

  1. Department of Organic Synthesis, Faculty of Engineering, Kyushu University, Fukuoka, 812, Japan

    Shigeori Takenaka, Kunihiko Dohtsu & Makoto Takagi

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  1. Shigeori Takenaka
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  2. Kunihiko Dohtsu
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  3. Makoto Takagi
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Takenaka, S., Dohtsu, K. & Takagi, M. Intercalator-Induced Gel-Electrophoretic Retardation of Synthetic Double-Stranded Oligonucleotides and Comigration of Intercalators. ANAL. SCI. 6, 139–141 (1990). https://doi.org/10.2116/analsci.6.139

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  • DOI: https://doi.org/10.2116/analsci.6.139

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