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On-line Enrichment and Measurement of Four Halogenated Phenols in Water Samples Using Pressure-Assisted Electrokinetic Injection–Tandem Mass Spectrometry

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Abstract

A rapid and sensitive method using pressure-assisted electrokinetic injection (PAEKI) as the on-line sample enrichment technique and electrospray–tandem mass spectrometry as the monitor has been developed for the determination of four halogenated phenols, 2,4,6-trichlorophenol, 2,4-dichlorophenol, 2,3,4,6-tetrachlorophenol and tetrabromobisphenol A, in water samples. In 8-min of injection, the four halogenated phenols in water samples were enriched up to several thousand times. With the aid of a solid-phase extraction clean-up procedure, the method achieved a detection limit in the range of 7.4 to 37.1 ng L–1 for the four phenols by multiple reaction monitoring in a negative mode. The overall recoveries for all four halogenated phenols in water samples were in the range of 68 to 114%. The good method repeatability has been demonstrated by the relative standard deviations (RSDs) of less than 10% for water samples spiked with standard mixtures. The four target phenols in all the water samples were below the detection limits.

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References

  1. S. R. Wild, S. J. Harrad, and K. C. Jones, Water Res., 1993, 27, 1527.

    Article  CAS  Google Scholar 

  2. R. H. Burttschell, A. A. Rosen, F. M. Middleton, and M. B. Ettinger, J. Am. Water Works Assoc., 1959, 51, 205.

    Article  Google Scholar 

  3. M. C. Quintana and L. Ramos, TrAC, Trends Anal. Chem., 2008, 27, 418.

    Article  CAS  Google Scholar 

  4. N. Alizadeh, H. Zarabadipour, and A. Mohammadi, Anal. Chim. Acta, 2007, 605, 159.

    Article  CAS  PubMed  Google Scholar 

  5. U. S. Environmental Protection Agency, “Method 604, Phenols, Federal Register, Part VIII, 40 CFR Part 136”, 1984.

  6. U. S. Environmental Protection Agency, “Method 625 Base/neutrals and Acids, Federal Register, Part VIII, 40 CFR Part 136”, 1984.

  7. U. S. Environmental Protection Agency, “Method 8041, Phenols by Gas Chromatography: Capillary Column Technique”, 1995.

  8. World Health Organization, “Environmental Health Criteria 172: Tetrabromobisphenol A and Derivatives, Geneva”, 1995.

  9. World Health Organization, “Environmental Health Criteria 192: Flame Retardants—General Introduction. Geneva”, 1997.

  10. A. Sjödin, H. Carlsson, K. Thuresson, S. Sjölin, Å. Bergman, and C. Östman, Environ. Sci. Technol., 2001, 35, 448.

    Article  PubMed  Google Scholar 

  11. E. Eljarrat and D. Barceló, TrAC, Trends Anal. Chem., 2004, 23, 727.

    Article  CAS  Google Scholar 

  12. T. Hayama, H. Yoshida, S. Onimaru, S. Yonekura, H. Kuroki, K. Todoroki, H. Nohta, and M. Yamaguchi, J. Chromatogr., B, 2004, 809, 131.

    Article  CAS  Google Scholar 

  13. I. A. Meerts, J. J. van Zanden, E. A. Luijks, I. van Leeuwen-Bol, G. Marsh, E. Jakobsson, A. Bergman, and A. Brouwer, Toxicol. Sci., 2000, 56, 95.

    Article  CAS  PubMed  Google Scholar 

  14. J. Legeler and A. Brouwer, Environ. Int., 2003, 29, 879.

    Article  Google Scholar 

  15. J. Regueiro, M. Llompart, E. Psillakis, J. C. Garcia-Monteagudoc, and C. Arcia-Ares, Talanta, 2009, 79, 1387.

    Article  CAS  PubMed  Google Scholar 

  16. H. Faraji, M. S. Tehrani, and S. W. Husain, J. Chromatogr., A, 2009, 1216, 8569.

    Article  CAS  PubMed  Google Scholar 

  17. O. Jáuregui, E. Moyano, and M. T. Galceran, J. Chromatogr., A, 1998, 823, 241.

    Article  Google Scholar 

  18. X. Ye, Z. Kuklenyik, L. L. Needham, and A. M. Calafat, Anal. Chem., 2005, 77, 5407.

    Article  CAS  PubMed  Google Scholar 

  19. M. N. Sarrión, F. J. Santos, E. Moyano, and M. T. Galceran, Rapid Commun. Mass Spectrom., 2003, 17, 39.

    Article  PubMed  Google Scholar 

  20. R. Wissiack, E. Rosenberg, and M. Grasserbauer, J. Chromatogr., A, 2000, 896, 159.

    Article  CAS  PubMed  Google Scholar 

  21. L. Xu and D. C. Spink, J. Chromatogr., B, 2007, 855, 159.

    Article  CAS  Google Scholar 

  22. A. Gentili, S. Marchese, and D. Perret, Trends Anal. Chem., 2008, 27, 888.

    Article  CAS  Google Scholar 

  23. O. Jáuregui, E. Moyano, and M. T. Galceran, J. Chromatogr., A, 2000, 896, 125.

    Article  PubMed  Google Scholar 

  24. A. Ma Gómez-Caravaca, V. Verardo, A. Segura-Carretero, M. F. Caboni, and A. Fernández-Gutiérrez, J. Chromatogr., A, 2008, 1209, 238.

    Article  Google Scholar 

  25. C.-Y. Tsai and G.-R. Her, J. Chromatogr., A, 1996, 743, 315.

    Article  CAS  Google Scholar 

  26. D. S. Burgi and R.-L. Chien, Anal. Chem., 1991, 63, 2042.

    Article  CAS  Google Scholar 

  27. R.-L. Chien and D. S. Burgi, Anal. Chem., 1992, 64, 489A.

    Article  CAS  Google Scholar 

  28. J. P. Quirino and S. Terabe, Science, 1998, 282, 465.

    Article  CAS  PubMed  Google Scholar 

  29. J. P. Quirino and S. Terabe, Anal. Chem., 2000, 72, 1023.

    Article  CAS  PubMed  Google Scholar 

  30. M. E. Swartz and M. Merion, J. Chromatogr., 1993, 632, 209.

    Article  CAS  Google Scholar 

  31. A. J. Tomlinson, W. D. Braddock, L. M. Benson, R. P. Oda, and S. Naylor, J. Chromatogr., B, 1995, 669, 67.

    Article  CAS  Google Scholar 

  32. K. Sueyoshi, F. Kitagawa, and K. Otsuka, Anal. Chem., 2008, 80, 1255.

    Article  CAS  PubMed  Google Scholar 

  33. Y.-L. Feng and J. Zhu, Anal. Chem., 2006, 78, 6608.

    Article  CAS  PubMed  Google Scholar 

  34. Y.-L. Feng, H. Lian, and J. Zhu, J. Chromatogr., A, 2007, 1148, 244.

    Article  CAS  PubMed  Google Scholar 

  35. Y.-L. Feng and J. Zhu, Electrophoresis, 2008, 29, 1965.

    Article  CAS  PubMed  Google Scholar 

  36. U. S. Environmental Protection Agency, “Chapter 5: Water Quality Conditions, Volunteer Stream Monitoring: A Methods Manual”, 1997.

  37. U. S. Environmental Protection Agency, “Method 528, Determination of Phenols in Drinking Water by Solid Phase Extraction and Capillary Column Gas Chromatography/ Mass Spectrometry (GC/MS)”, 2000.

  38. S. Chu, G. D. Haffner, and R. J. Letcher, J. Chromatogr., A, 2005, 1097, 25.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Exposure and Biomonitoring Division, Health Canada, AL: 0800C, EHC, Tunney’s Pasture, Ottawa, Ontario, K1A 0K9, Canada

    Huijuan Zhang, Jiping Zhu & Yong-Lai Feng

Authors
  1. Huijuan Zhang
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  2. Jiping Zhu
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  3. Yong-Lai Feng
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Correspondence to Yong-Lai Feng.

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Zhang, H., Zhu, J. & Feng, YL. On-line Enrichment and Measurement of Four Halogenated Phenols in Water Samples Using Pressure-Assisted Electrokinetic Injection–Tandem Mass Spectrometry. ANAL. SCI. 26, 1157–1162 (2010). https://doi.org/10.2116/analsci.26.1157

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  • DOI: https://doi.org/10.2116/analsci.26.1157

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