Abstract
Identifying and measuring the ammonia gas that emanates from human skin, which we called skin gas, has been achieved using a modified gas chromatographic system with a nitrogen-selective detector (flame-thermoionic detector: FTD). The skin gas is collected with a home-made sampling probe or bag, which is used to cover the skin surface of a subject’s wrist, or a finger, for 5 min. It was proved that ammonia was present in skin gas for healthy persons and patients with hepatic disease. The average amounts of ammonia were 1.7 ± 0.4 and 2.7 ± 0.8 ng/cm2; furthermore, there was a significant difference between them (p < 0.05). In addition, the ammonia levels present in skin gas were correlated with that in blood (r = 0.64, p 0.05).
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Nose, K., Mizuno, T., Yamane, N. et al. Identification of Ammonia in Gas Emanated from Human Skin and Its Correlation with That in Blood. ANAL. SCI. 21, 1471 (2005). https://doi.org/10.2116/analsci.21.1471
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DOI: https://doi.org/10.2116/analsci.21.1471