Skip to main content
SpringerLink
Log in

Electrochemical Determination of Titratable Acidity for the Discrimination of Schisandrae Chinensis Fructus and Schisandrae Sphenantherae Fructus

  • Published:
Analytical Sciences Aims and scope Submit manuscript

Abstract

A simple electrochemical procedure has been developed for determining the titratable acidity in Schisandrae Chinensis Fructus (SCF) and Schisandrae Sphenantherae Fructus (SSF) by means of reduction of quinone in the presence of acid compounds. To measure a voltammogram, a test solution was prepared by mixing a water extract from SCF or SSF and an electrolyte cocktail containing 3,5-di-tert-butyl-1,2-benzoquinone and NaCl. The quantitative results of titratable acidity in the SCF and SSF samples by the present voltammetry were in good agreement with those by neutralization titration using 0.1 M NaOH (r2 = 0.980): y = 1.003x + 0.010, where the y- and x-axes were the titratable acidity obtained by the present voltammetry and the neutralization titration, respectively. Further, the titratable acidities in the SSF samples were significantly lower than those in the SCF samples (p < 0.01). From these findings, we show that the titratable acidity is useful as an indicator to discriminate between SCF and SSF. Moreover, a prototype of electrochemical portable sensor for on-site analysis has been provided to perform this procedure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Pharmacopoeia of the People’s Republic of China, 2015, China Pharmacopoeia Committee, Beijing.

  2. W. D. Zhang, Q. Wang, Y. Wang, X. J. Wang, J. X. Pu, Y. Gu, and R. Wang, J. Sep. Sci., 2012, 35, 2203.

    Article  CAS  PubMed  Google Scholar 

  3. S. Maeda, K. Sudo, M. Aburada, Y. Ikeya, H. Taguchi, I. Yoshioka, and M. Harada, Yakugaku Zasshi, 1981, 101, 1030.

    Article  CAS  PubMed  Google Scholar 

  4. K. T. Liu, T. Cresteil, S. Columelli, and P. Lesca, Chem. Biol. Interact., 1982, 39, 315.

    Article  CAS  PubMed  Google Scholar 

  5. Y. Kiso, M. Tohkin, H. Hikino, Y. Ikeya, and H. Taguchi, Planta Med., 1985, 4, 331.

    Article  Google Scholar 

  6. Y. H. Lin, X. L. Wang, Y. Wang, and C. Z. Zhang, J. Dalian Inst. Light Ind., 2004, 23, 270.

    Google Scholar 

  7. L. Zhang and X. Niu, Acta Acad. Med. Sin., 1991, 13, 13.

    CAS  Google Scholar 

  8. F. Ahumada, M. A. Trincado, J. A. Arellano, J. Hancke, and G. Wikman, Phytother. Res., 1991, 5, 29.

    Article  Google Scholar 

  9. T. Huang, P. Shen, and Y. Shen, J. Chromatogr. A, 2005, 1066, 239.

    Article  CAS  PubMed  Google Scholar 

  10. K. Y. Kim, S. K. Ku, K. W. Lee, C. H. Song, and W. G. An, J. Ethnopharmacol., 2018, 212, 175.

    Article  PubMed  Google Scholar 

  11. United States Pharmacopeia and National Formulary USP 41-NF-36, 2018, The United States Pharmacopeial Convention, Rockville, MD.

  12. The Japanese Pharmacopoeia, 17th ed., 2016, The Ministry of Health, Labour and Welfare, Tokyo.

  13. X. Y. Li, M. Yang, J. Y. Huang, X. X. Yu, M. Q. Zhao, Z. K. Liang, Z. S. Xie, and X. J. Xu, J. Pharm. Anal., 2013, 3, 429.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. S. N. Zhang and S. X. Wu, J. Chin. Med. Mater., 2007, 30, 118.

    CAS  Google Scholar 

  15. P. Jiang, Y. Lub, and D. Chena, J. Pharm. Biomed. Anal., 2016, 131, 263.

    Article  CAS  PubMed  Google Scholar 

  16. R. Oshima, A. Kotani, M. Kuroda, K. Yamamoto, Y. Mimaki, and H. Hakamata, J. Nat. Med., 2018, 72, 399.

    Article  CAS  PubMed  Google Scholar 

  17. A. Kotani, F. Kusu, K. Takamura, and H. Hakamata, J. Electrochem. Soc., 2020, 167, 037517.

    Article  CAS  Google Scholar 

  18. A. Kotani, T. Masuda, C. Yoshioka, A. Hirashima, H. Hakamata, and F. Kusu, J. Brew. Soc. Jpn., 2015, 110, 13.

    Article  CAS  Google Scholar 

  19. A. Kotani, Y. Miyaguchi, D. Harada, and F. Kusu, Anal. Sci., 2003, 19, 1473.

    Article  CAS  PubMed  Google Scholar 

  20. A. Kotani, K. Kitamura, F. Kusu, K. Yamamoto, and H. Hakamata, Electroanalysis, 2018, 30, 2988.

    Article  CAS  Google Scholar 

  21. J. L. Hancke, R. A. Burgos, and F. Ahumada, Fitoterapia, 1990, 70, 451.

    Article  Google Scholar 

  22. Y. Lu and D. F. Chen, J. Chromatogr. A, 2009, 1216, 1980.

    Article  CAS  PubMed  Google Scholar 

  23. D. Zou, J. Wang, B. Zhang, S. Xie, Q. Wang, K. Xu, and R. Lin, Molecules, 2015, 20, 21373.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. T. Murakami, M. Nagasawa, H. Itokawa, and H. Inatomi, Shoyakugaku Zasshi, 1965, 19, 44.

    Google Scholar 

  25. H. Taguchi, J. Tradit. Sino. Jpn. Med., 1985, 6, 65.

    CAS  Google Scholar 

  26. L. Li, Y. Xiao, D. Yu, Y. Ma, W. Huang, G. Tian, and L. Chen, Zhongguo Zhongyao Zazhi, 2011, 36, 3286.

    CAS  PubMed  Google Scholar 

  27. L. Lu, Anal. Sci., 2020, 36, 127.

    Article  CAS  PubMed  Google Scholar 

  28. J. Dang, H. Cui, X. Li, and J. Zhang, Anal. Sci., 2019, 35, 979.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

This work was supported in part by JSPS KAKENHI Grant Number JP18K05181.

Author information

Authors and Affiliations

  1. Department of Analytical Chemistry, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, 192-0392, Japan

    Akira Kotani, Kazuhiro Yamamoto & Hideki Hakamata

Authors
  1. Akira Kotani
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Maki Kaneko
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Koichi Machida
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Kazuhiro Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Hideki Hakamata
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Akira Kotani.

Electronic supplementary material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kotani, A., Kaneko, M., Machida, K. et al. Electrochemical Determination of Titratable Acidity for the Discrimination of Schisandrae Chinensis Fructus and Schisandrae Sphenantherae Fructus. ANAL. SCI. 36, 1003–1008 (2020). https://doi.org/10.2116/analsci.20P049

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2116/analsci.20P049

Keywords

Search

Navigation