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Flow-Injection Determination of Ornidazole by Chemiluminescence Detection Basedon a Luminol-Ferricyanide Reaction

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Abstract

A flow-injection analysis (FIA) with a chemiluminescence detection method was developed for the determination of ornidazole based on the inhibition intensity of chemiluminescence from the luminol-ferricyanide system. Under the condition of 1. 0 × 10–3 mol/L luminol and 5. 0 × 10–6 mol/L potassium ferricyanide, the response to the concentration of ornidazole is linear from 0. 2 µg ml–1 to 10 µg ml–1, and a detection limit of 0. 05 µg ml–1 can be obtained. This method has been successfully applied to the determination of ornidazole in pharmaceutical preparations.

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Authors and Affiliations

  1. Institute of Analytical Science, Department of Chemistry, Southwest Normal University, Beibei, Chongqing, 400715, P. R. China

    Yi Lv, Zhujun Zhang, Deyong He & Yufei Hu

Authors
  1. Yi Lv
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  2. Zhujun Zhang
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  3. Deyong He
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  4. Yufei Hu
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Correspondence to Zhujun Zhang.

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Lv, Y., Zhang, Z., He, D. et al. Flow-Injection Determination of Ornidazole by Chemiluminescence Detection Basedon a Luminol-Ferricyanide Reaction. ANAL. SCI. 19, 625–626 (2003). https://doi.org/10.2116/analsci.19.625

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  • DOI: https://doi.org/10.2116/analsci.19.625

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