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Electrocatalytic Response of Dopamine at a Metallothioneins Self-Assembled Gold Electrode

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Abstract

The metallothioneins (MT) self-assembled monolayer modified gold electrode (MT/Au) is demonstrated to catalyze the electrochemical response of dopamine (DA) by cyclic voltammetry. A pair of well-defined redox waves was obtained and the calculated standard rate constant (ks) is 6.97 × 10–3 cm s–1 (20°C) at the self-assembled electrode. The electrode reaction is a quasi-reversible process. The oxidation peak of DA can be used to determine the concentration of DA. The peak current and the concentration of DA follow a linear relationship in the range of 2.0 × 10–5 M to 8.0 × 10–4 M. The detection limit is 6.0 × 10–6 M. By ac impedance spectroscopy, the apparent electron transfer rate constant (kapp) of Fe(CN)63–/Fe(CN)64– at the MT/Au electrode was obtained as 2.0 × 10–5 cm s–1. The MT/Au was characterized with grazing angle FT-IR spectroscopy and contact angle goniometry.

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Authors and Affiliations

  1. Department of Chemistry, Peking University, Beijing, 100871, People’s Republic of China

    Qian Wang, Nanqiang Li & Wenqing Wang

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  1. Qian Wang
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  2. Nanqiang Li
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  3. Wenqing Wang
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Correspondence to Nanqiang Li.

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Wang, Q., Li, N. & Wang, W. Electrocatalytic Response of Dopamine at a Metallothioneins Self-Assembled Gold Electrode. ANAL. SCI. 18, 635–639 (2002). https://doi.org/10.2116/analsci.18.635

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  • DOI: https://doi.org/10.2116/analsci.18.635

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