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Protein Structural Characterization by Scanning Tunneling Microscopy with Electrochemistry

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Abstract

The structure characterization of proteins or enzymes by STM on electrochemically prepared HOPG surface studied in this laboratory is reviewed. The serial structures of Hb were observed. The differences between the denaturation and inactivation of HRP were investigated by in situ and ex situ STM. The structural variation of Hb in an organic solvent was imaged while protein denaturation was easily observed in a polar solvent.

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References

  1. G. Binnig, H. Rohrer, Ch. Gerber, and E. Wel, Phys. Rev. Lett., 1982, 49, 57.

    Article  Google Scholar 

  2. J. Zhang, G. Zhu, and E. Wang, Surf. Sci., 1996, 4, L530.

    Article  Google Scholar 

  3. Z. Chen, J. Li, and E. Wang, J. Electroanal. Ch., 1994, 373, 83.

    Article  CAS  Google Scholar 

  4. B. Zhang, Y. Zhao, D. Yang, and E. Wang, J. ter. Sci. Lett., 1995, 14, 1275.

    Article  CAS  Google Scholar 

  5. B. Zhang and E. Wang, J. Electroanal. Chem., 1995, 388, 207.

    Article  Google Scholar 

  6. B. Zhang and E. Wang, Electrochim. Acta, 1995, 2627.

    Google Scholar 

  7. F. Li, B. Zhang, E. Wang, and S. Dong, J. E troanal. Chem., 1997, 422, 27.

    CAS  Google Scholar 

  8. B. Zhang and E. Wang, Chin. J. Chem., 1995, 13 93.

    Google Scholar 

  9. Z. Chen and E. Wang, Sci. China. Ser. B., 1994, 337.

    Google Scholar 

  10. J. L. Wang and E. Wang, Chem. Res. Chin. Univers. 1994, 10, 72.

    Google Scholar 

  11. J. Zhang, Q. Chi, S. Dong, and E. Wang, J. C m. Soc., Faraday Trans., 1996, 92, 1913.

    Article  CAS  Google Scholar 

  12. J. Zhang, Q. Chi, E. Wang, and S. Dong, E trochim. Acta, 1995, 40, 733.

    Article  CAS  Google Scholar 

  13. J. Li, B. Zhang, and E. Wang, Acta. Chim. Sinic 1994, 52, 646.

    CAS  Google Scholar 

  14. Q. Chi, J. Zhang, S. Dong, and E. Wang, J. em. Soc. Faraday Trans., 1994, 90, 2057.

    Article  CAS  Google Scholar 

  15. B. Zhang and E. Wang, Nanobiology, 1996, 4, 8

    Google Scholar 

  16. J. Zhang, Q. Chi, B. Zhang, S. Dong, and E. Wang, Electroanalysis, 1998, 10, 738.

    Article  CAS  Google Scholar 

  17. J. Zhang, Q. Chi, B. Zhang, S. Dong, and E. Wang, Surf. Sci., 1994, 321, L195.

    Article  CAS  Google Scholar 

  18. J. Zhang, Q. Chi, S. Dong, and E. Wang, J. em. Soc. Faraday Trans., 1995, 91, 1471.

    Article  CAS  Google Scholar 

  19. J. Zhang, Q. Chi, S. Dong, and E. Wang, Bioe rochem. Bioener., 1996, 39, 267.

    Article  CAS  Google Scholar 

  20. B. Zhang, Y. Zhu, S. Dong, and E. Wang, Inte J. Biol. Macromol., 1997, 21, 251.

    Article  CAS  Google Scholar 

  21. Y. F. He and E. K. Wang, Acta Chim. Sinica 1997, 55, 801.

    CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Laboratory of Electroanalytical Chemistry and National Analytical Research Center of Electrochemistry and Spectroscopy, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, P. R. China

    Erkang Wang, Hongda Wang & Zhuang Li

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  1. Erkang Wang
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  2. Hongda Wang
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  3. Zhuang Li
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Wang, E., Wang, H. & Li, Z. Protein Structural Characterization by Scanning Tunneling Microscopy with Electrochemistry. ANAL. SCI. 16, 205–209 (2000). https://doi.org/10.2116/analsci.16.205

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  • DOI: https://doi.org/10.2116/analsci.16.205

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