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Immunocryosurgery for basal cell carcinoma: impact on circulating CD4+ CD25high T regulatory cells and serum cytokines

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European Journal of Dermatology

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References

  1. Kaporis HG, Guttman-Yassky E, Lowes M, et al. Human basal cell carcinoma is associated with Foxp3+ T cells in a Th2 dominant microenvironment. J Invest Dermatol 2007; 127: 2391–8.

    Article  CAS  Google Scholar 

  2. Gaitanis G, Bassukas ID. Immunocryosurgery for non-superficial basal cell carcinoma: a prospective, open-label phase III study for tumours ≤2 cm in diameter. Acta Derm Venereol 2014; 94: 38–44.

    Article  Google Scholar 

  3. Gaitanis G, Alexopoulos EC, Bassukas ID. Cryosurgery is more effective in the treatment of primary, non-superficial basal cell carcinomas when applied during and not prior to a five week imiquimod course: a randomized, prospective, open-label study. Eur J Dermatol 2011; 21: 952–8.

    Article  Google Scholar 

  4. Nomikos K, Lampri E, Spyridonos P, Bassukas ID. Alterations in the inflammatory cells infiltrating basal cell carcinomas during immunocryosurgery. Arch Dermatol Res 2019; 311: 499–504.

    Article  CAS  Google Scholar 

  5. Klein SL, Flanagan KL. Sex differences in immune responses. Nat Rev Immunol 2016; 16: 626–38.

    Article  CAS  Google Scholar 

  6. Gaitanis G, Bassukas ID. Intralesional bevacizumab as in-add adjuvant to immunocryosurgery for locally advanced basal cell carcinoma. J Eur Acad Dermatol Venereol 2014; 28: 1117–21.

    Article  CAS  Google Scholar 

  7. Bassukas ID, Gaitanis G. Combination of cryosurgery and topical imiquimod: does timing matter for successful immunocryosurgery? Cryobiology 2009; 59: 116–7.

    Article  Google Scholar 

  8. Skov L, Allen MH, Bang B, et al. Basal cell carcinoma is associated with high TNF-alpha release but nor with TNF-alpha polymorphism at position-308. Exp Dermatol 2003; 12: 772–6.

    Article  CAS  Google Scholar 

  9. Sobjanek M, Zabłotna M, Bień E, et al. Clinical significance of IL-2 and IL-10 gene polymorphisms and serum levels in patients with basal-cell carcinoma. Biomark Med 2016; 10: 185–95.

    Article  CAS  Google Scholar 

  10. Bassukas ID, Ganiatsa A, Gaitanis G. Health-related quality of life associated with immunocryosurgery, a minimally invasive modality, for cervicofacial basal cell carcinoma. Eur J Dermatol 2019; 29: 234–6.

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Skin and Venereal Diseases, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece

    Georgios Gaitanis, Areti Ganiatsa & Ioannis D. Bassukas

  2. Molecular Biology Unit, Laboratory of Haematology, University Hospital of Ioannina, Ioannina, Greece

    Georgios Vartholomatos & Achilleas Karamoutsios

  3. Department of Pharmacology, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece

    Periklis Pappas

Authors
  1. Georgios Gaitanis
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  2. Areti Ganiatsa
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  3. Georgios Vartholomatos
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  4. Achilleas Karamoutsios
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  5. Periklis Pappas
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  6. Ioannis D. Bassukas
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Corresponding author

Correspondence to Ioannis D. Bassukas.

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Disclosure

Funding sources: this study was partially supported by the University of Ioannina; Research Committee Account 22195. Conflicts of interest: none.

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Gaitanis, G., Ganiatsa, A., Vartholomatos, G. et al. Immunocryosurgery for basal cell carcinoma: impact on circulating CD4+ CD25high T regulatory cells and serum cytokines. Eur J Dermatol 30, 605–606 (2020). https://doi.org/10.1684/ejd.2020.3864

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  • DOI: https://doi.org/10.1684/ejd.2020.3864

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