References
Gibbs S, Harvey I, Sterling J, Stark R. Local treatments for cutaneous warts: systematic review. BMJ 2002; 325:461.
Lass-Flörl C. Triazole antifungal agents in invasive fungal infections: a comparative review. Drugs 2011; 71: 2405–19.
Liu R, Li J, Zhang T, et al. Itraconazole suppresses the growth of glioblastoma through induction of autophagy: involvement of abnormal cholesterol trafficking. Autophagy 2014; 10: 1241–55.
Kim J, Aftab B, Tang J, et al. Itraconazole and arsenic trioxide inhibit hedgehog pathway activation and tumor growth associated with acquired resistance to smoothened antagonists. Cancer Cell 2013; 23: 23–4.
Teglund S, Toftgard R. Hedgehog beyond medulloblastoma and basal cell carcinoma. Biochim Biophys Acta 2010; 1805: 181–208.
Vishnoi K, Mahata S, Tyagi A, et al. Cross-talk between human papillomavirus oncoproteins and hedgehog signaling synergistically promotes stemness in cervical cancer cells. Sci Rep 2016; 6: 34377.
Chen H, Wang J, Yang H, Chen D, Panpan Li. Association between FOXM1 and hedgehog signaling pathway in human cervical carcinoma by tissue microarray analysis. Oncol Lett 2016; 12: 2664–73.
El-Nabarawy EA, El-Hanafy GM, Rashed LA, Yasin FS. Expression of angiopoietin-1, angiopoietin-2, and their receptor Tie2 in verruca vulgaris (common skin warts). Int J Dermatol 2016; 55: e327–31.
Kim J, Tang JY, Gong R, et al. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell 2010; 17: 388–99.
Strating JR, van der Linden L, Albulescu L, et al. Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein. Cell Rep 2015; 10: 600–15.
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Table S1.
Clinical characteristics of the patients with different treatment modalities and outcome.
About this article
Cite this article
El Khoury, R., Tomb, R. & Stephan, F. Itraconazole: an incidental clearance of recalcitrant warts?. Eur J Dermatol 28, 264–266 (2018). https://doi.org/10.1684/ejd.2018.3232
Published:
Issue Date:
DOI: https://doi.org/10.1684/ejd.2018.3232