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Multiple neurological abnormalities, including pontine hemorrhage, multiple sclerosis and aseptic meningitis, during anti-TNF-α therapy in psoriatic arthritis

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References

  1. Nestle FO, Kaplan DH, Barker J. Psoriasis. N Engl J Med 2009; 361: 496–509.

    Article  PubMed  CAS  Google Scholar 

  2. Saad AA, Symmons DP, Noyce PR, Ashcroft DM. Risks and benefits of tumor necrosis factor-alpha inhibitors in the management of psoriatic arthritis: systematic review and metaanalysis of randomized controlled trials. J Rheumatol 2008; 35: 883–90.

    PubMed  CAS  Google Scholar 

  3. Andreadou E, Kemanetzoglou E, Brokalaki C, et al. Demyelinating Disease following Anti-TNFa Treatment: A Causal or Coincidental Association? Report of Four Cases and Review of the Literature. Case Rep Neurol Med 2013; 2013: 671935.

    PubMed  CAS  PubMed Central  Google Scholar 

  4. Almoallim H, Al-Ghamdi Y, Almaghrabi H, Alyasi O. Anti-Tumor Necrosis Factor-alpha Induced Systemic Lupus Erythematosus. Open Rheumatol J 2012; 6: 315–9.

    Article  PubMed  CAS  PubMed Central  Google Scholar 

  5. Bernatsky S, Renoux C, Suissa S. Demyelinating events in rheumatoid arthritis after drug exposures. Ann Rheum Dis 2010; 69: 1691–3.

    Article  PubMed  CAS  Google Scholar 

  6. Marotte H, Charrin JE, Miossec P. Infliximab-induced aseptic meningitis. Lancet 2001; 358: 1784.

    Article  PubMed  CAS  Google Scholar 

  7. Robinson WH, Genovese MC, Moreland LW. Demyelinating and neurologic events reported in association with tumor necrosis factor alpha antagonism: by what mechanisms could tumor necrosis factor alpha antagonists improve rheumatoid arthritis but exacerbate multiple sclerosis? Arthritis Rheum 2001; 44: 1977–83.

    Article  PubMed  CAS  Google Scholar 

  8. Hua Y, Wu J, Keep RF, Nakamura T, Hoff JT, Xi G. Tumor necrosis factor-alpha increases in the brain after intracerebral hemorrhage and thrombin stimulation. Neurosurgery 2006; 58: 542–50.

    Article  PubMed  Google Scholar 

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Correspondence to Atsushi Otsuka.

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Honda, Y., Otsuka, A., Egawa, G. et al. Multiple neurological abnormalities, including pontine hemorrhage, multiple sclerosis and aseptic meningitis, during anti-TNF-α therapy in psoriatic arthritis. Eur J Dermatol 25, 487–488 (2015). https://doi.org/10.1684/ejd.2015.2558

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