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European Journal of Dermatology

, Volume 25, Issue 3, pp 255–260 | Cite as

Restless legs syndrome in psoriasis: an unexpected comorbidity

  • Caroline Schell
  • Ramona Schleich
  • Florian Walker
  • Amir S. Yazdi
  • Holger Lerche
  • Martin Röcken
  • Detlef Axmann
  • Kamran Ghoreschi
  • Franziska C. Eberle
Clinical report

Abstract

Background

Restless legs syndrome (RLS) is characterized by unpleasant sensations in the legs and an uncontrollable urge to move them in order to gain relief. Higher frequencies of RLS have been reported in systemic lupus, multiple sclerosis, rheumatoid arthritis and atopic dermatitis.

Objectives

Since the disease-related stress present in psoriasis is similar to the stress of those diseases, we aimed to study the frequency of RLS in a German cohort of patients with psoriasis.

Methods

300 patients with psoriasis and 300 healthy controls were evaluated for RLS symptoms in this study.

Results

While 17% (n = 51) of patients with psoriasis reported symptoms of RLS, only 4% (n = 12) of individuals without psoriasis suffered from RLS symptoms (95% confidence interval: 0.08–0.18, p<0.01). In patients with psoriasis and RLS the average RLS score was 16.0 ± 9.2 whereas individuals with RLS in the control group had an average RLS score of 13.5 ± 7.1.

Conclusions

Our findings indicate an increased frequency of RLS in patients with psoriasis, suggesting screening patients with psoriasis for the presence of RLS as a well-treatable co-morbidity.

Keywords

psoriasis quality of life restless legs syndrome 

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Copyright information

© John Libbey Eurotext 2015

Authors and Affiliations

  • Caroline Schell
    • 1
  • Ramona Schleich
    • 2
  • Florian Walker
    • 2
  • Amir S. Yazdi
    • 2
  • Holger Lerche
    • 1
  • Martin Röcken
    • 2
  • Detlef Axmann
    • 3
  • Kamran Ghoreschi
    • 2
  • Franziska C. Eberle
    • 2
  1. 1.Department of Neurology and EpileptologyHertie Institute for Clinical Brain ResearchTübingenGermany
  2. 2.Department of Dermatology, Oral Medicine and Maxillofacial SurgeryEberhard Karls University TübingenTübingenGermany
  3. 3.Center of Dentistry, Oral Medicine and Maxillofacial SurgeryEberhard Karls University TübingenTübingenGermany

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