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When wrinkles appear on the immune system can it be reversed?

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European Cytokine Network Aims and scope

Abstract

During aging, physiological and physical frailty occur, which is accompanied by a decline in adaptive and innate immunity, termed ‘immunosenescence’ characterized by marked changes in the composition, function, and competence of the human immune system. Moreover, the capabilities of the immune system to defend the human body against infections, to detect and destruct malignant or autoreactive cells decline, resulting in an increase in the susceptibility to infection, development of cancer, as well as autoimmune disorders. The study of age-related changes in immune function is an important area of investigation. In this review, the function of the immune system during aging, as well as the different ways to rejuvenate the aging immune system, is explored, as medical intervention, balanced nutrition, and a healthy life style will be discussed.

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Authors and Affiliations

  1. Medical Physiology Department, National Research Centre (NRC), Dokki, Egypt

    Hiba Sibaii & Salwa Refat El-Zayat

  2. Department of Basic Sciences, Biology Division, Deanship of Preparatory Year, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam, Saudi Arabia

    Mona Khalil

Authors
  1. Hiba Sibaii
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  2. Salwa Refat El-Zayat
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  3. Mona Khalil
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Correspondence to Hiba Sibaii.

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Sibaii, H., El-Zayat, S.R. & Khalil, M. When wrinkles appear on the immune system can it be reversed?. Eur Cytokine Netw 31, 1–17 (2020). https://doi.org/10.1684/ecn.2020.0441

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  • DOI: https://doi.org/10.1684/ecn.2020.0441

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