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European Journal of Dermatology

, Volume 27, Issue 6, pp 573–578 | Cite as

Comparison of allergen responses based on the TRUE Test and IQ Chamber system in Korean patients

  • Won Joo Kwon
  • Joo Yeon Ko
  • Young Suck Ro
  • Myung Hwa Kim
  • Byung Soo Kim
  • Hye One Kim
  • Jae Hui Nam
  • Ga-Young Lee
  • Mi Youn Park
  • Sang Wook Son
  • Jun Mo Yang
  • Dong Hun Lee
  • Ai Young Lee
  • Jun Young Lee
  • Sung Eun Chang
  • Hae Young Choi
  • Eun Joo ParkEmail author
Investigative report
  • 51 Downloads

Abstract

Background

A comparison between responses to allergens based on the TRUE Test® (TT) and IQ® Chamber (IQC) in Europeans has been previously reported, however, no such study has been performed in Asians.

Objectives

To compare allergen responses using the TT and IQC (using the Korean standard series) in order to gather more information regarding the positive response rates for each allergen and the clinical value of IQC.

Materials & methods

Suspected contact dermatitis patients were enrolled and tested with 18 allergens using the TT and IQC.

Results

The test was performed in 214 patients. Simultaneous positive results for both tests were recorded in 242 cases (positive concordance rate: 66.7%). IQC yielded more positive results. Allergens with a high positive concordance rate were nickel sulphate (82.1%), thimerosal (78.6%), and p-phenylenediamine (73.3%). IQC mostly showed similar or higher positive rates than TT, with high concordance.

Conclusions

We recommend the IQC method as a screening test in patients with suspected contact dermatitis. To compensate for possible false positive results, careful history taking and a different patch test should be performed when appropriate.

Key words

concordance IQ® Chamber Korean standard series patch test TRUE Test® 

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Copyright information

© JLE/Springer 2018

Authors and Affiliations

  • Won Joo Kwon
    • 1
  • Joo Yeon Ko
    • 2
  • Young Suck Ro
    • 2
  • Myung Hwa Kim
    • 3
  • Byung Soo Kim
    • 4
  • Hye One Kim
    • 5
  • Jae Hui Nam
    • 6
  • Ga-Young Lee
    • 6
  • Mi Youn Park
    • 7
  • Sang Wook Son
    • 8
  • Jun Mo Yang
    • 9
  • Dong Hun Lee
    • 10
  • Ai Young Lee
    • 11
  • Jun Young Lee
    • 12
  • Sung Eun Chang
    • 13
  • Hae Young Choi
    • 14
  • Eun Joo Park
    • 1
    Email author
  1. 1.Department of DermatologyHallym University Sacred Heart HospitalAnyangKorea
  2. 2.Department of DermatologyHanyang University College of MedicineSeoulKorea
  3. 3.Department of DermatologyDankook University College of MedicineCheonanKorea
  4. 4.Department of DermatologyBusan National University College of MedicineBusanKorea
  5. 5.Department of DermatologyHallym University College of MedicineSeoulKorea
  6. 6.Department of Dermatology, Kangbuk Samsung HospitalSungkyunkwan University School of MedicineSeoulKorea
  7. 7.Department of DermatologyNational Medical CenterSeoulKorea
  8. 8.Korea University College of MedicineKorea University Ansan HospitalAnsanKorea
  9. 9.Department of DermatologySungkyunkwan University College of MedicineSeoulKorea
  10. 10.Department of DermatologySeoul National University College of MedicineSeoulKorea
  11. 11.Department of DermatologyDongguk University College of MedicineKyungjuKorea
  12. 12.College of MedicineCatholic University of KoreaSeoulKorea
  13. 13.Department of DermatologyUniversity of Ulsan College of MedicineSeoulKorea
  14. 14.Department of DermatologyEwha Womans University College of MedicineSeoulKorea

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