Economic Botany

, Volume 61, Issue 3, pp 246–255 | Cite as

Doctrine of Signatures: An explanation of medicinal plant discovery or Dissemination of knowledge?

  • Bradley C. Bennett
Research Articles

Abstract

The Doctrine of Signatures (DOS) is found throughout the world. Most scholars dismiss it as a “primitive” or “prescientific” idea. Despite its long history, the doctrine has had little critical review. A careful evaluation of signatures suggests four things. (1) There is no evidence that morphological plant signatures ever led to the discovery of medicinal properties. Considering DOS in this manner is unproductive and largely untestable. (2) Signatures are post hoc attributions rather than a priori clues to the utility of medicinal plants. (3) It is productive to redefine signatures to include organoleptic properties associated with therapeutic value. Plants with strong odors or bitter tastes, for example, commonly are found in pharmacopoeias. (4) DOS should be considered for what it primarily is—a way of disseminating information. DOS fundamentally is a mnemonic and, therefore, is exceedingly valuable in traditional cultures.

Key Words

Doctrine of signatures medicinal plant selection medicinal plants mnemonic organoleptic properties transmission of knowledge Paracelsus signatures 

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Literature Cited

  1. Ankli A., O. Sticher, and M. Heinrich. 1999. Yuacatec Maya Medicinal Plants versus Nonmedicinal Plants: Indigenous Plant Characterization and Selection. Human Ecology 27:557–580.CrossRefGoogle Scholar
  2. Arber, A. 1988. Herbals: Their Origin and Evolution, a Chapter in the History of Botany 1470–1670. 3rd Edition. Cambridge University Press, New York (orig. publication 1912).Google Scholar
  3. Baerts-Lehmann, M. and J. Lehmann. n.d. Prelude Medicinal Plants. http://www.metafro.be/prelude (25 September 2006).Google Scholar
  4. Bailey, L. H., E. Z. Bailey, and the staff of the Liberty Hyde Bailey Hortorium. 1976 Hortus Third, MacMillan Publishing Company, New York.Google Scholar
  5. Balée, W. 1994. Footprints in the Forest. Ka’apor Ethnobotany—The Historical Ecology of Plant Utilization by an Amazonian People. Columbia University Press, New York.Google Scholar
  6. Barford, A. S., and L. P. Kvist. 1996. Comparative Ethnobotanical Studies of the Amerindian Groups in Coastal Ecuador. Biologiske Skrifter 46:1–166.Google Scholar
  7. Bellavite, P., A. Conforti, V. Piasere, and R. Ortolani. 2005. Immunology and Homeopathy. 1. Historical Background. Evidence-Based Complementary and Alternative Medicine 2:441–452.CrossRefPubMedGoogle Scholar
  8. Bennett, B. C., C. R. Bell, and R. T. Boulware. 1990. Geographic Variation in Alkaloid Content of Sanguinaria canadensis (Papaveraceae). Rhodora 92:57–69.Google Scholar
  9. —, M. A. Baker, and P. Gómez. 2002. Ethnobotany of the Shuar of Eastern Ecuador. Advances in Economic Botany 14:1–299.Google Scholar
  10. Berlin, B. 1992. Ethnobiological Classification: Principles of Categorization of Plants and Animals in Traditional Societies. Princeton University Press, Princeton, New Jersey.Google Scholar
  11. Billing, J., and P. W Sherman. 1998. Antimicrobial Functions of Spices: Why Some Like It Hot. Quarterly Review of Biology 73:3–49.CrossRefPubMedGoogle Scholar
  12. Boericke, W. 2004. A Compend of the Principles of Homeopathy as Taught by Hahnemann and Verified by a Century of Clinical Application. Kessinger Publishing, Whitefish, Montana.Google Scholar
  13. Böhme, J. 1621. The Signature of All Things [Signatura Rerum]. Translated by William Law. http://pegasus.cc.ucf.edu/≈janzb/boehme/sigrer1.htm (24 March 2006).Google Scholar
  14. Browner, C. H. 1985. Plants Used for Reproductive Health in Oaxaca, Mexico. Economic Botany 39:482–504.Google Scholar
  15. Buchanan, S. 1991. The Doctrine of Signatures: A Defense of Theory in Medicine. 2nd Edition. University of Illinois Press, Urbana, Illinois (orig. publication 1938).Google Scholar
  16. Carlson, A. W. 1986. Ginseng: America’s Botanical Drug Connection to the Orient. Economic Botany 40:232–249.Google Scholar
  17. Chaturvedi, P. 2005. Role of Momordica charantia in Maintaining the Normal Levels of Lipids and Glucose in Diabetic Rats Fed a High-Fat and Low-Carbohydrate Diet. British Journal of Biomedical Science 62:124–126.PubMedGoogle Scholar
  18. Chistokhodova, N., C. Nguyen, T. Calvino, I. Kachirskaia, G. Cunningham G, and D. Howard Miles. 2002. Antithrombin Activity of Medicinal Plants from Central Florida. Journal of Ethnopharmacology 81:277–280.CrossRefPubMedGoogle Scholar
  19. Clarke, J. H. 1923. A Dictionary of Practical Materia Medica. Homoeopathic Publishing Co., London. http://www.homeoint.org/morrell/clarke/paracelsus.htm (20 March 2006).Google Scholar
  20. Clubb, L. G. 1965. Giambattista Della Porta, Dramatist. Princeton University Press, Princeton, New Jersey.Google Scholar
  21. Cole, W. 2004. The Art of Simpling: An Introduction to the Knowledge and Gathering of Plants. Kessinger Publishing, Whitefish, Montana (orig. publication 1656).Google Scholar
  22. Cooper, E. L. 2004. Review of 12th International Congress of Oriental Medicine (2003). Plenary Lecture—Chieh—Fu Chen, Traditional, Modern and Alternative Medicines. Evidence-Based Complementary and Alternative Medicine 1:103–106.CrossRefGoogle Scholar
  23. Crollius, O. 1669. A Treatise of Oswaldus Crollius of Signatures of Internal Things; or, a True and Lively Anatomy of the Greater and Lesser World, Printed for John Starkey and Thomas Passenger, London. [Transcribed by Sean Brooks.] http://www.levity.com/alchemy/croll_signatures.html (15 March 2006).Google Scholar
  24. Culpeper, N. 1652. The English Physitian [sic]: Or an Astrologo-Physical Discourse of the Vulgar Herbs of this Nation. Peter Cole, London. http://www.med.yale.edu/library/historical/culpeper/culpeper.htm (10 March 2006).Google Scholar
  25. Dafni, A., and E. Lev. 2002. The Doctrine of Signatures in Present-Day Israel. Economic Botany 56:328–334.CrossRefGoogle Scholar
  26. Davis, E. W., and J. A. Yost. 1983. The Ethnomedicine of the Waorani of Amazonian Ecuador. Journal of Ethnopharmacology 9:273–297.CrossRefPubMedGoogle Scholar
  27. Debus, A. G. 1973. A Further Note on Paligenesis: The Account of Ebenezer Sibly in the Illustration of Astrology (1792). Isis 64:226–230.CrossRefGoogle Scholar
  28. della Porta, G. 1658. The First Book of Natural Magick: Wherein Are Searched out the Causes of Things which Produce Wonderful Effects. http://homepages.tscnet.com/omard1/jportac1.html#Chap11Bk1 (14 March 2006) (orig. publication 1558).Google Scholar
  29. Dioscorides, P. 2000. De materia medica. Ibidis Press, Johannesburg, South Africa. (Translated by T. A. Osbaldeston). http://www.cancerlynx.com/BOOKONEAROMATICS.PDF (25 March 2006) (orig. publication A.D. 65).Google Scholar
  30. Dodoens, R. 1583. Stirpium Historiae Pemplades VI, Sive Libri XXX. Antverpiae, Antwerp.Google Scholar
  31. Donald, M. 1997. Precis of Origins of the Modern Mind: Three Stages in the Evolution of Culture and Cognition. Behavioral and Brain Sciences 16:737–791.CrossRefGoogle Scholar
  32. Duke, J. n.d. Dr. Duke’s Phytochemical and Ethnobotanical Databases. http://www.ars-grin.gov/duke/ (20 September 2006).Google Scholar
  33. Eggleston, E. 1901. The Transit of Civilization from England to America in the Seventeenth Century. D. Appleton and Company, New York. http://www.dinsdoc.com/eggleston-2-2.htm#xv (16 March 2006).Google Scholar
  34. Encyclopæadia Britannica. 2006a. Pliny the Elder. Encyclopæadia Britannica Online, Academic Edition. http://search.eb.com/eb/article-5784 (23 March 2006).Google Scholar
  35. Encyclopæadia Britannica. 2006b. Herbal. Encyclopæadia Britannica Online, Academic Edition. http://search.eb.com/eb/article-9040104 (23 March 2006).Google Scholar
  36. Etkin, N. L. 1988. Ethnopharmacology: Biobehavioral Approaches in the Anthropological Study of Indigenous Medicines. Annual Review of Anthropology 17:23–42.CrossRefGoogle Scholar
  37. Gerard, J. 1975. The Herbal or General History of Plants. Dover Publications, New York (orig. publication 1597).Google Scholar
  38. Gould, S. J. 2000. The Jew and the Jew Stone. Natural History 109 (June): 26–39.Google Scholar
  39. Grieve, M. 1971. A Modern Herbal: The Medicinal, Culinary, Cosmetic and Economic Properties, Cultivation and Folk-Lore of Herbs, Grasses, Fungi, Shrubs & Trees with Their Modern Scientific Uses. Dover Publications. New York (orig. publication 1931).Google Scholar
  40. Hahnemann, S. 1825. Materia medica pura [translated R. E. Dudgeon, 1992]. B. Jain Publishers, New Delhi, India.Google Scholar
  41. Hazlett, D. L. 1986. Ethnobotanical Observation from Cabecar and Guaymí Settlements in Central America. Economic Botany 40:339–352.Google Scholar
  42. James, Tamarra. (n.d.). The Doctrine of Signatures, Recognize Herbs. http://www.holysmoke.org/wb/wb0081.htm (27 March 2006).Google Scholar
  43. Kaplan, L., M. Taylor, and J. W. Thieret. 2001. Economic Botany: Index to Volumes 1–50 (1947–1996), The New York Botanical Garden Press, New York.Google Scholar
  44. Karimi, G., H. Hosseinzadeh, and N. Ettehad. 2004. Evaluation of the Gastric Antiulcerogenic Effects of Portulaca oleracea L. Extracts in Mice. Phytotherapy Research 18:484–487.CrossRefPubMedGoogle Scholar
  45. Keightley, A. 1925. Studies in Paracelsus. Theosophical Quarterly 23:147 327–349.Google Scholar
  46. Kreig, M. B. 1964. Green Medicine. Bantam Books, New York.Google Scholar
  47. Leonti, M., O. Sticher, and M. Heinrich. 2002. Medicinal Plants of the Popoluca, Mexico: Organoleptic Properties as Indigenous Selection Criteria. Journal of Ethnopharmacology 81:307–315.CrossRefPubMedGoogle Scholar
  48. Levetin, E., and K. McMahon. 1999. Plants and Society. 2nd Edition. MCB/McGraw-Hill, Boston, Massachusetts.Google Scholar
  49. Mabberley, D. J. 1987. The Plant Book: A Portable Dictionary of the Higher Plants. Cambridge University Press. New York.Google Scholar
  50. Maycock, P. P., Jr. 1991. Introduction to the Second Edition. Pages xv–xxix in S. Buchanan, The Doctrine of Signatures: A Defense of Theory in Medicine. 2nd Edition. University of Illinois Press, Urbana, Illinois.Google Scholar
  51. Medeiros, I. A., M. R. Santos, N. M. Nascimento, and J. C. Duarte. 2006. Cardiovascular Effects of Sida cordifolia Leaves Extract in Rats. Fitoterapia 77:19–27.CrossRefPubMedGoogle Scholar
  52. Milton, J. 2002. Paradise Lost. Penguin Classics, New York (orig. publication, 1667).Google Scholar
  53. Moerman, D. E. 2002. Meaning, Medicine and the ‘Placebo Effect,’ Cambridge University Press, Cambridge, United Kingdom.Google Scholar
  54. Moerman, D.E. n.d. Native American Ethnobotany. http://herb.umd.umich.edu. (30 August 2006).Google Scholar
  55. Mooney, J. 1992. History, Myths, and Sacred Formulas of the Cherokees. Historical Images Press, Asheville, North Carolina (orig. publication 1900). http://www.cherokeenationmexico.com/sacred_formulas.html (22 March 2006).Google Scholar
  56. Nöth, W. 1998. Ecosemiotics. Sign Systems Studies 26:332–343.Google Scholar
  57. Ogungbamila, F. O., and G. Samuelsson. 1990. Smooth Muscle Relaxing Flavonoids from Alchornea cordifolia. Acta Pharmaceutica Nordica 2:421–422.PubMedGoogle Scholar
  58. Panese, F. 2003. The “Doctrine of Signatures” and Graphical Technologies at the Dawn of Modernity. [in French]. Gesnerus 60:6–24.PubMedGoogle Scholar
  59. Plotkin, M. J. 2000. Medicine Quest. Viking Penguin, New York.Google Scholar
  60. Powell, J. W. 1901. Introduction in F. H. Cushing, Zuñi Folk Tales. http://www.sacred-texts.com/nam/zuni/zft/index.htm (20 March 2006).Google Scholar
  61. Quinlan, M. B., R. J. Quinlan, and J. M. Nolan. 2002. Ethnophysiology and Herbal Treatments of Intestinal Worms in Dominica, West Indies. Journal of Ethnopharmacology 80(1):75–83.CrossRefPubMedGoogle Scholar
  62. Ray, J. 1717. The Wisdom of God Manifested in the Works of Creation. 7th Edition. Printed by R. Harbin, for William Innys, at the Prince’s-Arms in St Paul’s Church Yard. http://www.jri.org.uk/ray/wisdom/index.htm (10 April 2007) (orig. pubication 1691).Google Scholar
  63. Read, B. E. 1927. Some Old Chinese Herbs Used in Obstetrical Practice. Journal of Obstetrics and Gynaecology 34:498–508.Google Scholar
  64. Reed, D. 2005a. Doctrine of Signatures. Wildflowers of the Southeastern United States. http://2bnthewild.com/S2.htm (27 March 2006).Google Scholar
  65. Reed, D. 2005b. Wild Comfrey (Cynoglossum virginianum). Wildflowers of the Southeastern United States. http://2bnthewild.com/index2.shtml (updated on 8/12/2001, 27 March 2006).Google Scholar
  66. Rowlings, J. K. 1999. Harry Potter and the Chamber of Secrets. Arthur A. Levine Books, New York.Google Scholar
  67. Saine, A. 2002. Drawing a Line in the Sand: Homeopathy or not Homeopathy? Journal of the American Institute of Homeopathy 95:69–88.Google Scholar
  68. Schultes, R. E., and R. F. Raffauf. 1990. The Healing Forest: Medicinal and Toxic Plants of the Northwest Amazonia. Dioscorides Press, Portland, Oregon.Google Scholar
  69. Schultes, R. E., and A. Hoftmann. 1980. The Botany and Chemistry of Hallucinogens. 2nd Edition. Charles C. Thomas, Springfield, Illinois.Google Scholar
  70. Shepard, G. H., Jr. 2002. Nature’s Madison Avenue: Sensory Cues as Mnemonic Devices in the Transmission of Medicinal Plant Knowledge among the Matisgenka and Yora of Peru. Pages 326–335 in J. R. Stepp, F. S. Wyndham and R. K. Zarger, eds., Ethnobiology and Biocultural Diversity. International Society of Ethnobiology, Athens, Georgia.Google Scholar
  71. Sherman, P. W., and J. Billing. 1999. Darwinian Gastronomy: Why We Use Spices. BioScience 49:453–463.CrossRefGoogle Scholar
  72. Simpson, B. B., and M. C. Ogorzaly. 2001. Economic Botany, Plants in Our World. 3rd Edition. McGraw Hill, Boston, Massachusetts.Google Scholar
  73. Stoss, M., C. Michels, E. Peter, R. Beutke, and R. W. Gorter. 2000. Prospective Cohort Trial of Euphrasia Single-Dose Eye Drops in Conjunctivitis. Journal of Alternative and Complementary Medicine 6: 499–508.CrossRefGoogle Scholar
  74. Sumner, J. 2000. The Natural History of Medicinal Plants. Timber Press, Portland, Oregon.Google Scholar
  75. Thiselton-Dyer, T. F. 1889. The Folk-Lore of Plants. Appelton & Co., New York. http://www.gutenberg.org/files/10118/10118-8.txt (24 March 2006).Google Scholar
  76. Touw, M. 1982. Roses in the Middle Ages. Economic Botany 36:71–83.Google Scholar
  77. Tyler, V. E. 1993. The Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies. 3rd Edition, Haworth Press, New York.Google Scholar
  78. — 1994. Herbs of Choice: The Therapeutic Use of Phytomedicinals. Haworth Press, New York.Google Scholar
  79. U.S. National Library of Medicine. n.d. PubMed. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?DB=pubmed (10 September 2006).Google Scholar
  80. Vane, J. R., and R. M. Botting. 1998. Anti-Inflammatory Drugs and Their Mechanism of Action. Inflammation Research 47 (Supplement 2): 78–87.CrossRefGoogle Scholar
  81. Vickery, A. R. 1981. Traditional Uses and Folklore of Hypericum in the British Isles. Economic Botany 35:289–295.Google Scholar

Copyright information

© The New York Botanical Garden 2007

Authors and Affiliations

  • Bradley C. Bennett
    • 1
  1. 1.Department of Biological Sciences and Center for Ethnobiology and Natural ProductsFlorida International UniversityMiami

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