概要
妊娠合并心脏病的发病率为0.5%~3.0%,是导致孕产妇死亡的非产科病因首位。而重度肺动脉高压的处理最为棘手,合并艾森曼格综合征的孕产妇死亡率高达30%~50%,剖宫产患者甚至达65%~75%。妊娠合并重度肺动脉高压属于妊娠禁忌,一旦诊断需尽快终止妊娠,能达足月妊娠者临床非常罕见。本文报道一例足月妊娠合并重度肺动脉高压和艾森曼格综合征患者的成功诊治,旨在提高产科医师对该合并症的重视和多学科管理,并提高对该疾病围手术期的精细诊疗水平。
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Acknowledgments
We acknowledge all the multidisciplinary members from Renji Hospital (Shanghai, China) for their dedication and support. This work was supported by the Natural Science Foundation of Science and Technology Commission of Shanghai Municipality (No. 22ZR1438700), China.
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Shibin HONG contributed to data analysis, writing and editing of the manuscript. Xin KANG contributed to data analysis. Ka U. LIO contributed to writing and editing of the manuscript. Yiping LE and Chuan WANG collected materials in the study. Jianhua LIN and Ning ZHANG conceived and designed the study, and revised the manuscript. The scientific guarantor of this publication is Ning ZHANG. All authors have read and approved the final manuscript, and therefore, have full access to all the data in the study and take responsibility for the integrity and security of the data.
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Shibin HONG, Xin KANG, Ka U. LIO, Yiping LE, Chuan WANG, Jianhua LIN, and Ning ZHANG declare that they have no conflict of interest.
All procedures followed were in accordance with the ethical standards of the Ethics Committee of Renji Hospital, Shanghai Jiao Tong University School of Medicine and with the Helsinki Declaration of 1975, as revised in 2008 (5). Ethical approval document was not required for the single case report in accordance with the Renji Hospital’s requirement. Informed consent was obtained from the patient for being included in the study. Additional informed consent was obtained from the patient for which identifying information is included in this article.
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Hong, S., Kang, X., Lio, K.U. et al. Multidisciplinary approach for the management of term pregnancy complicated by Eisenmenger syndrome. J. Zhejiang Univ. Sci. B 24, 89–93 (2023). https://doi.org/10.1631/jzus.B2200368
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DOI: https://doi.org/10.1631/jzus.B2200368