Gastrointestinal involvement of COVID-19 and potential faecal transmission of SARS-CoV-2

COVID-19 胃肠道感染和 SARS-CoV-2 潜在的粪便传播

概要

多中心临床数据显示, 部分 2019 冠状病毒病 (COVID-19) 患者存在腹泻、 恶心和呕吐等胃肠道症状, 相关研究也证实严重急性呼吸综合征冠状病毒 2 型 (SARS-CoV-2) 能够在胃肠道复制并从粪便中分离到活的 SARS-CoV-2. 在意大利和澳大利亚等国, 其未处理的污水中检测到了 SARS-CoV-2, 且根据污水中 SARS-CoV-2 的含量估算出的 COVID-19 患者与临床实际感染患者较为一致. 粪便中的 SARS-CoV-2 能够挥发存在于气溶胶中并保持较长时间的活力, 故当人们暴露在被 SARS-CoV-2 污染的环境中即可能经 “粪便-气溶胶-粘膜” 途径感染 SARS-CoV-2, 而当人们食用被 SARS-CoV-2 污染的食物或水则可能经 “粪-口” 途径感染 SARS-CoV-2. 因此, 对可能被 COVID-19 患者粪便污染的环境或物品进行严格管理和有效消毒对控制 COVID-19 大流行具有重要意义.

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Authors

Contributions

Jin-bo LIU, Min SONG, and Zong-lin LI devised the original idea for the comment. Min SONG, Zong-lin LI, and Ye-jiang ZHOU drafted the original manuscript. Gang TIAN, Ting YE, Zhang-rui Zeng, Jian DENG, Hong WAN, and Qing LI did the literature search and provided ideas for perfection. All authors critically reviewed the article and Jin-bo LIU gave the final approval for the version to be published.

Corresponding author

Correspondence to Jin-bo Liu.

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Min SONG, Zong-lin LI, Ye-jiang ZHOU, Gang TAN, Ting YE, Zhang-rui ZENG, Jian DENG, Hong WAN, Qing LI, and Jin-bo LIU declare that they have no conflict of interest.

This article does not contain any studies with human or animal subjects performed by any of the authors.

Project supported by the Key Research and Development of Science and Technology Projects of Luzhou (Special Project Fund for Emergency Research), China

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Song, M., Li, Zl., Zhou, Yj. et al. Gastrointestinal involvement of COVID-19 and potential faecal transmission of SARS-CoV-2. J. Zhejiang Univ. Sci. B 21, 749–751 (2020). https://doi.org/10.1631/jzus.B2000253

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关键词

  • 2019 冠状病毒病 (COVID-19)
  • 严重急性呼吸综合征冠状病毒 2 型 (SARS-CoV-2)
  • 胃肠道感染
  • 粪便传播