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Depolymerized konjac glucomannan: preparation and application in health care

解聚型魔芋葡甘露聚糖的制备以及生理活性研究的进展

Journal of Zhejiang University-SCIENCE B volume 19, pages 505–514 (2018)Cite this article

Abstract

Konjac glucomannan (KGM) is a water-soluble polysaccharide obtained from the roots and tubers of konjac plants. Recently, a degraded product of KGM, depolymerized KGM (DKGM), has attracted attention because of its low viscosity, improved hydrophily, and favorable physiological functions. In this review, we describe the preparation of DKGM and its prebiotic effects. Other health benefits of DKGM, covering antioxidant and immune activity, are also discussed, as well as its safety. DKGM could be a candidate for use as a tool for the treatment of various diseases, including intestinal flora imbalance, and oxidative- and immune-related disorders.

概要

魔芋葡甘露聚糖是从魔芋块茎中提取的一种高分 子水溶性多糖。近些年研究表明,其解聚产物, 除了具有高溶解性和低粘度等良好的理化性质 外,还具有调节微生物菌群结构、抗氧化、免疫 调节等多种生理活性。本文重点综述了解聚型葡 甘露聚糖的制备方法以及菌群调节功能。除此之 外,对其抗氧化、免疫调节功能以及安全性评价 也进行了全面的总结,为解聚型葡甘露聚糖的研 究与应用提供一定的依据与思路。

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Authors and Affiliations

  1. School of Pharmaceutical, Jiangnan University, Wuxi, 214122, China

    Min Jiang, Heng Li & Jin-song Shi

  2. Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Pharmaceutical Science, Jiangnan University, Wuxi, 214122, China

    Jin-song Shi

  3. National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, 214122, China

    Zheng-hong Xu

  4. School of Biotechnology, Jiangnan University, Wuxi, 214122, China

    Zheng-hong Xu

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  1. Min Jiang
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  2. Heng Li
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  3. Jin-song Shi
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  4. Zheng-hong Xu
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Correspondence to Jin-song Shi.

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Project supported by the National First-Class Discipline Program of Light Industry Technology and Engineering (Nos. LITE2018-18 and LITE2018-11) of China, the Transformation Project for Major Scientific and Technological Achievements in Jiangsu Province (No. BA2015006), the Industry-Academia Cooperation Innovation Fund Project of Jiangsu Province (No. BY2016022-19), and the National Key Technologies R&D Program of China for the 12th Five-year Plan (No. 2012BAD33B06)

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Jiang, M., Li, H., Shi, Js. et al. Depolymerized konjac glucomannan: preparation and application in health care. J. Zhejiang Univ. Sci. B 19, 505–514 (2018). https://doi.org/10.1631/jzus.B1700310

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