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Subglottic adenoid cystic carcinoma mistaken for asthma

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Abstract

Adenoid cystic carcinoma rarely occurs within the subglottic larynx. In this study, a case of subglottic adenoid cystic carcinoma was reported. A 54 year-old Chinese woman developed a sudden onset of chest distress and cough worsening after physical exertion, and was diagnosed with, and treated as, bronchial asthma. Regular anti-asthmatic therapy did not improve the symptoms. Until a sudden dyspnea, a cervicothoracic computerized tomography (CT) revealed that her upper airway was obstructed by a laryngeal tumor. The patient was diagnosed with a subglottic adenoid cystic carcinoma and treated with complete surgical excision and adjuvant radiation therapy. Follow-up endoscopy and laryngeal magnetic resonance imaging (MRI) at six months showed no recurrence of the tumor. The diagnosis of subglottic adenoid cystic carcinoma should be considered in patients who are characterized by dyspnea, cough, and stridor, but do not respond to regular anti-asthmatic therapy.

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References

  • Allen, M.S., 1993. Malignant tracheal tumours. Mayo Clin. Proc., 68(7):680–684.

    PubMed  CAS  Google Scholar 

  • Aydin, O., Ustundag, E., Iseri, M., Ercin, C., 2008. Laryngeal adenoid cystic carcinoma in an adolescent. Kulak Burun Bogaz Ihtis Derg., 18(5):319–322.

    PubMed  Google Scholar 

  • Dahm, J.D., Sessions, D.G., Paniello, R.C., Harvev, J., 1998. Primary subglottic cancer. Laryngoscope, 108(5):741–746. [doi:10.1097/00005537-199805000-00022]

    Article  PubMed  CAS  Google Scholar 

  • Damborenea Tajada, J., Campos del Alamo, M.A., Marín García, J., Leache Pueyo, J., Liorente Arenas, E., Fernández Liesa, R., 1999. Adenoid cystic carcinoma of the larynx: case report and literature review. An. Otorrinolaringol. Ibero Am., 26(3):257–263.

    PubMed  CAS  Google Scholar 

  • Ganly, I., Patel, S.G., Coleman, M., Ghossein, R., Carlson, D., Shah, J.P., 2006. Malignant minor salivary gland tumors of the larynx. Arch. Otolaryngol. Head Neck Surg., 132(7):767–770. [doi:10.1001/archotol.132.7.767]

    Article  PubMed  Google Scholar 

  • Garas, J., McGuirt, W.F., 2006. Squamous cell carcinoma of the subglottis. Am. J. Otolaryngol., 27(1):1–4. [doi:10.1016/j.amjoto.2005.05.004]

    Article  PubMed  Google Scholar 

  • Goyal, A., Tyagi, I., Tewari, P., Agarwal, S.K., Syal, R., 2005. Management of difficult airway in intratracheal tumor surgery. BMC Ear Nose Throat Disorders, 5(1):4 [doi:10.1186/1472-6815-5-4]

    Article  Google Scholar 

  • Horiuchi, J., Shibuya, H., Suzuki, S., Takeda, M., Takagi, M., 1987. The role of radiotherapy in the management of adenoid cystic carcinoma of the head and neck. Int. J. Radiat. Oncol. Biol. Phys., 13(8):1135–1141.

    PubMed  CAS  Google Scholar 

  • Javadi, M., Bafrouee, F.M., Monseni, M., 2002. Laryngeal adenoid cystic carcinoma in a child: a case report. Ear Nose Thorat J., 81(1):34–35.

    Google Scholar 

  • Kokturk, N., Demir, N., Kervan, F., Ninc, E., Koybasioqlu, A., Turktas, H., 2004. A subglottic mass mimicking near-fatal asthma: a challenge of diasnosis. J. Emerg. Med., 29(1): 104–105.

    Google Scholar 

  • Kokturk, N., Demircan, S., Kurul, C., Turktas, H., 2005. Tracheal adenoid cystic carcinoma masquerading asthma: a case report. BMC Pulm. Med., 19(4):10. [doi:10.1186/1471-2466-4-10]

    Google Scholar 

  • Morais, P.D., Cortejoso, H.A., Borau, C.M., 1999. Adenoid cystic carcinoma of the larynx. Acta Otorrinolaringol. Esp., 50(8):660–663.

    Google Scholar 

  • Shi, M.L., 1987. X-ray diagnosis of trachea and large tracheal primary non-squamous epithelial carcinoma: analysis of 23 cases. Chin. J. Tumour, 9:208–210 (in Chinese).

    CAS  Google Scholar 

  • Stack, P.S., Steckler, R.M., 1990. Tracheal neurilemmoma:case report and review of the literature. Head Neck, 12(5): 436–439. [doi:10.1002/hed.2880120512]

    Article  PubMed  CAS  Google Scholar 

  • Sur, R.K., Donde, B., Levin, V., Pacella, J., Kotzen, J., Cooper, K., Hale, M., 1997. Adenoid cystic carcinoma of the salivary glands: a review of 10 years. Laryngoscope, 107(9): 1276–1280. [doi:10.1097/00005537-199709000-00022]

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Otorhinolaryngology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, 310009, China

    Hua-lin Wang, Lin Xu & Fu-jun Li

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  1. Hua-lin Wang
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  2. Lin Xu
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  3. Fu-jun Li
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Correspondence to Hua-lin Wang.

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Wang, Hl., Xu, L. & Li, Fj. Subglottic adenoid cystic carcinoma mistaken for asthma. J. Zhejiang Univ. Sci. B 10, 707–710 (2009). https://doi.org/10.1631/jzus.B0920071

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  • DOI: https://doi.org/10.1631/jzus.B0920071

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