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A new germacranolide fromCarpesium cernuum

  • Materials & Chemical Engineering
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Abstract

As a part of our interest in biologically active germacranolides from the genusCarpesium (Compositae), we have investigated the constituents ofCarpesium cernuum. This paper reports the isolation and structural elucidation of a new germacranolide, cernolide A (Compound 1), from the herb. The structure of Compound 1 was determined as 2α,3β-dihydroxy-9-angeloxygermacra-4-en-6,12-olide on the basis of spectral evidence. The skeleton of Compound 1 was elucidation by IR, MS,1H and13CNMR, COSY, HMQC and HMBC experiments. The stereochemistry of Compound 1 was deduced by ROESY spectral data. Finally, the procedures of extraction and isolation were described in detail.

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Authors and Affiliations

  1. Department of Chemistry, Zhejiang University, 310027, Hangzhou, China

    Cao Jian-xin & Pan Yuan-jiang

  2. Zhejiang Hisun Pharmaceutical Co., Ltd, 318000, Taizhou, China

    Cao Jian-xin, Xu Chong-yang, Huang Li-xia, Ma Shu-hong, Dai Chang-liang & Gao Wan-wan

Authors
  1. Cao Jian-xin
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  2. Pan Yuan-jiang
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  3. Xu Chong-yang
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  4. Huang Li-xia
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  5. Ma Shu-hong
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  6. Dai Chang-liang
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  7. Gao Wan-wan
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Correspondence to Cao Jian-xin.

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Jian-xin, C., Yuan-jiang, P., Chong-yang, X. et al. A new germacranolide fromCarpesium cernuum . J Zheijang Univ Sci A 6, 640–642 (2005). https://doi.org/10.1631/jzus.2005.A0640

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  • DOI: https://doi.org/10.1631/jzus.2005.A0640

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