Journal of Zhejiang University SCIENCE B

, Volume 11, Issue 11, pp 842–847

Pure word deafness associated with extrapontine myelinolysis

  • Ren-jing Zhu
  • Zhi-su Lv
  • Chun-lei Shan
  • Ming-wei Xu
  • Ben-yan Luo
Case Report

DOI: 10.1631/jzus.B1000200

Cite this article as:
Zhu, R., Lv, Z., Shan, C. et al. J. Zhejiang Univ. Sci. B (2010) 11: 842. doi:10.1631/jzus.B1000200

Abstract

Extrapontine myelinolysis and pure word deafness are very uncommon disorders. Here, we report a case of a 19-year-old woman who suffered from osmotic demyelination syndrome with coincidence of typical pure word deafness. As a consequence of rapid correction of hyponatremia, the patient demonstrated an initial onset of cortical deafness, and then progressed to generalized auditory agnosia, which eventually developed into confined verbal auditory agnosia (pure word deafness). Bilateral extrapontine myelinolysis was confirmed using brain magnetic resonance imaging. This case suggests that verbal and nonverbal stimuli may involve separate thalamocortical pathways.

Key words

Pure word deafness Auditory agnosia Osmotic demyelination syndrome Extrapontine myelinolysis Cortical deafness 

CLC number

R74 

Copyright information

© Zhejiang University and Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Ren-jing Zhu
    • 1
    • 2
  • Zhi-su Lv
    • 1
    • 3
  • Chun-lei Shan
    • 4
    • 5
  • Ming-wei Xu
    • 1
  • Ben-yan Luo
    • 1
  1. 1.Department of Neurology, the First Affiliated Hospital, School of MedicineZhejiang UniversityHangzhouChina
  2. 2.Department of Neurology, Zhongshan HospitalXiamen UniversityXiamenChina
  3. 3.Department of Ultrasonography, Children’s Hospital, School of MedicineZhejiang UniversityHangzhouChina
  4. 4.Laboratory for Higher Brain Function, Institute of PsychologyChinese Academy of SciencesBeijingChina
  5. 5.Department of Rehabilitation Medicinethe First Affiliated Hospital of Nanjing Medical UniversityNanjingChina

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