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Simultaneous pH and glucose sensing and its relation in a non-enzymatic glucose sensor

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Abstract

We explore glucose sensitivity as a function of pH in the electrochemical non-enzymatic sensor. The employed sensor consisted of a Cu/CuO working electrode, an Ag/AgCl reference electrode, and a graphite counter electrode. A minimum pH value of 12.5 was determined for glucose sensing in the 0–8 mM range, and the maximum glucose sensitivity of 304 µA/mMcm2 was obtained at a pH of 13. The pH sensing capabilities of the system were also explored to determine its viability as a correction variable for glucose detection with the sample's pH, obtaining a pH sensitivity of 40 mV/pH in the 11.0–13.5 range.

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Acknowledgments

The authors thank CONAHCYT for funding the research, project FORDECYT No. 297497 and No. 312048 (LANITEM). The authors are grateful for the facilities granted using CONMAD CIDESI’s infrastructure.

Funding

CONAHCYT financially supports this work with the projects FORDECYT No. 297497 and No. 312048 (LANITEM).

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Authors and Affiliations

  1. Centro de Ingeniería y Desarrollo Industrial, Avenida Playa Pie de la Cuesta #702, 76125, Santiago de Querétaro, Querétaro, Mexico

    Pablo Tirado Cantu, Jesus Javier Alcantar Peña, Alexis Cruz Zabalegui, A. M. Jocelyn, Gilberto Martínez Saucedo, Daniela Díaz Alonso & I. R. Chávez-Urbiola

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  1. Pablo Tirado Cantu
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  2. Jesus Javier Alcantar Peña
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  3. Alexis Cruz Zabalegui
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  4. A. M. Jocelyn
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  5. Gilberto Martínez Saucedo
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  6. Daniela Díaz Alonso
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  7. I. R. Chávez-Urbiola
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Contributions

PT: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing—original draft, review & editing; DD: Conceptualization, Funding acquisition, Project administration, Project administration, Resources, Supervision, Validation, Visualization, Writing—original draft, review & editing. AC: Conceptualization, Funding acquisition, Methodology, Project administration, Project administration, Resources, Supervision; JA & IRC-U: Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing—original draft, review & editing; G. Olayo: Methodology, Resources, review & editing; J-AM: Methodology, Resources, review & editing; GM: Methodology, review & editing.

Corresponding author

Correspondence to I. R. Chávez-Urbiola.

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Tirado Cantu, P., Alcantar Peña, J., Cruz Zabalegui, A. et al. Simultaneous pH and glucose sensing and its relation in a non-enzymatic glucose sensor. MRS Communications 14, 96–102 (2024). https://doi.org/10.1557/s43579-023-00506-3

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