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Hybrid materials approaches for bioelectronics

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Abstract

Bioelectronic systems are emerging technologies with unique capabilities for establishing bidirectional biophysical and biochemical interfaces to soft living tissues. Applications range from tools for biomedical research on organoids and animal models to sensing and therapeutic platforms for addressing patient needs. Recent advances in materials science, materials processing techniques, and assembly/integration methods establish the foundations for progress in this area, with a growing collection of successful examples of translation into commercial products. This article summarizes our own work in this area, with an emphasis on hybrid approaches that combine both organic and inorganic materials into engineered composite structures optimized to support functional requirements, including physical/chemical levels of biocompatibility, high-performance electronic/microfluidic operation, tissue-like mechanical properties and geometries, and in some cases, fully bioresorbable designs and/or three-dimensional (3D) layouts. System-level examples that leverage these ideas span (1) epidermal platforms that probe the electrical, thermal, mechanical, and chemical properties of the skin and underlying physiological processes for diagnostic purposes; (2) implantable devices that combine sensors and therapeutic actuators under closed-loop feedback control through intimate interfaces to various tissues/organs; (3) bioresorbable electronic systems as temporary implants that support a desired operational time frame and then harmlessly degrade within the body; and (4) 3D mesoscale networks that integrate with tissue constructs across volumetric spaces for multimodal neuromodulation, sensing, and manipulation. We conclude with an overview of the current state of the field and a summary of research opportunities in hybrid materials approaches as the basis for continued advances in bioelectronics.

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References

  1. K.W. Cho, S.H. Sunwoo, Y.J. Hong, J.H. Koo, J.H. Kim, S. Baik, T. Hyeon, D.H. Kim, Chem. Rev. 122, 5068 (2022)

    CAS  Google Scholar 

  2. Q.S. Yang, Z.Y. Hu, J.A. Rogers, Acc. Mater. Res. 2, 1010 (2021)

    CAS  Google Scholar 

  3. E.M. Song, J.H. Li, S.M. Won, W.B. Bai, J.A. Rogers, Nat. Mater. 19, 590 (2020)

    CAS  Google Scholar 

  4. D.T. Simon, E.O. Gabrielsson, K. Tybrandt, M. Berggren, Chem. Rev. 116, 13009 (2016)

    CAS  Google Scholar 

  5. S. Xu, Z. Yan, K.I. Jang, W. Huang, H.R. Fu, J. Kim, Z. Wei, M. Flavin, J. McCracken, R. Wang, A. Badea, Y. Liu, D.Q. Xiao, G.Y. Zhou, J. Lee, H.U. Chung, H.Y. Cheng, W. Ren, A. Banks, X.L. Li, U. Paik, R.G. Nuzzo, Y.G. Huang, Y.H. Zhang, J.A. Rogers, Science 347, 154 (2015)

    CAS  Google Scholar 

  6. J.A. Fan, W.H. Yeo, Y.W. Su, Y. Hattori, W. Lee, S.Y. Jung, Y.H. Zhang, Z.J. Liu, H.Y. Cheng, L. Falgout, M. Bajema, T. Coleman, D. Gregoire, R.J. Larsen, Y.G. Huang, J.A. Rogers, Nat. Commun. 5, 3266 (2014)

    Google Scholar 

  7. S.R. Krishnan, T.R. Ray, A.B. Ayer, Y.J. Ma, P. Gutruf, K. Lee, J.Y. Lee, C. Wei, X. Feng, B. Ng, Z.A. Abecassis, N. Murthy, I. Stankiewicz, J. Freudman, J. Stillman, N. Kim, G. Young, C. Goudeseune, J. Ciraldo, M. Tate, Y.G. Huang, M. Potts, J.A. Rogers, Sci. Transl. Med. 10, eaat8437 (2018)

    Google Scholar 

  8. L.Z. Xu, S.R. Gutbrod, Y.J. Ma, A. Petrossians, Y.H. Liu, R.C. Webb, J.A. Fan, Z.J. Yang, R.X. Xu, J.J. Whalen, J.D. Weiland, Y.G. Huang, I.R. Efimov, J.A. Rogers, Adv. Mater. 27, 1731 (2015)

    CAS  Google Scholar 

  9. K.I. Jang, H.U. Chung, S. Xu, C.H. Lee, H.W. Luan, J. Jeong, H.Y. Cheng, G.T. Kim, S.Y. Han, J.W. Lee, J. Kim, M. Cho, F.X. Miao, Y.Y. Yang, H.N. Jung, M. Flavin, H. Liu, G.W. Kong, K.J. Yu, S.I. Rhee, J. Chung, B. Kim, J.W. Kwak, M.H. Yun, J.Y. Kim, Y.M. Song, U. Paik, Y.H. Zhang, Y. Huang, J.A. Rogers, Nat. Commun. 6, 6566 (2015)

    Google Scholar 

  10. H.U. Chung, B.H. Kim, J.Y. Lee, J. Lee, Z.Q. Xie, E.M. Ibler, K. Lee, A. Banks, J.Y. Jeong, J. Kim, C. Ogle, D. Grande, Y. Yu, H. Jang, P. Assem, D. Ryu, J.W. Kwak, M. Namkoong, J.B. Park, Y. Lee, D.H. Kim, A. Ryu, J. Jeong, K. You, B.W. Ji, Z.J. Liu, Q.Z. Huo, X. Feng, Y.J. Deng, Y.S. Xu, K.I. Jang, J. Kim, Y.H. Zhang, R. Ghaffari, C.M. Rand, M. Schau, A. Hamvas, D.E. Weese-Mayer, Y.G. Huang, S.M. Lee, C.H. Lee, N.R. Shanbhag, A.S. Paller, S. Xu, J.A. Rogers, Science 363, 947 (2019)

    Google Scholar 

  11. H.D. Bai, S. Li, R.F. Shepherd, Adv. Funct. Mater. 31(39), 2009364 (2021)

    CAS  Google Scholar 

  12. X.G. Yu, Z.Q. Xie, Y. Yu, J. Lee, A. Vazquez-Guardado, H.W. Luan, J. Ruben, X. Ning, A. Akhtar, D.F. Li, B.W. Ji, Y.M. Liu, R.J. Sun, J.Y. Cao, Q.Z. Huo, Y.S. Zhong, C. Lee, S. Kim, P. Gutruf, C.X. Zhang, Y.G. Xue, Q.L. Guo, A. Chempakasseril, P.L. Tian, W. Lu, J. Jeong, Y. Yu, J. Cornman, C. Tan, B. Kirn, K. Lee, X. Feng, Y.G. Huang, J.A. Rogers, Nature 575(7783), 473 (2019)

    CAS  Google Scholar 

  13. Y.H. Jung, J.Y. Yoo, A. Vazquez-Guardado, J.H. Kim, J.T. Kim, H.W. Luan, M. Park, J. Lim, H.S. Shin, C.J. Su, R. Schloen, J. Trueb, R. Avila, J.K. Chang, D.S. Yang, Y. Park, H. Ryu, H.J. Yoon, G. Lee, H. Jeong, J.U. Kim, A. Akhtar, J. Cornman, T.I. Kim, Y.G. Huang, J.A. Rogers, Nat. Electron. 5, 621 (2022)

    Google Scholar 

  14. R.C. Webb, A.P. Bonifas, A. Behnaz, Y.H. Zhang, K.J. Yu, H.Y. Cheng, M.X. Shi, Z.G. Bian, Z.J. Liu, Y.S. Kim, W.H. Yeo, J.S. Park, J.Z. Song, Y.H. Li, Y.G. Huang, A.M. Gorbach, J.A. Rogers, Nat. Mater. 12, 1078 (2013)

    CAS  Google Scholar 

  15. D.S. Yang, R. Ghaffari, J.A. Rogers, Science 379, 760 (2023)

    CAS  Google Scholar 

  16. A. Koh, D. Kang, Y. Xue, S. Lee, R.M. Pielak, J. Kim, T. Hwang, S. Min, A. Banks, P. Bastien, M.C. Manco, L. Wang, K.R. Ammann, K.-I. Jang, P. Won, S. Han, R. Ghaffari, U. Paik, M.J. Slepian, G. Balooch, Y.G. Huang, J.A. Rogers, Sci. Transl. Med. 8(366), 366ra165 (2016). https://doi.org/10.1126/scitranslmed.aaf2593

    Article  Google Scholar 

  17. T.R. Ray, M. Ivanovic, P.M. Curtis, D. Franklin, K. Guventurk, W.J. Jeang, J. Chafetz, H. Gaertner, G. Young, S. Rebollo, J.B. Model, S.P. Lee, J. Ciraldo, J.T. Reeder, A. Hourlier-Fargette, A.J. Bandodkar, J. Choi, A.J. Aranyosi, R. Ghaffari, S.A. McColley, S. Haymond, J.A. Rogers, Sci. Transl. Med. 13(587), eabd8109 (2021). https://doi.org/10.1126/scitranslmed.abd8109

    Article  Google Scholar 

  18. L.B. Baker, J.B. Model, K.A. Barnes, M.L. Anderson, S.P. Lee, K.A. Lee, S.D. Brown, A.J. Reimel, T.J. Roberts, R.P. Nuccio, J.L. Bonsignore, C.T. Ungaro, J.M. Carter, W.H. Li, M.S. Seib, J.T. Reeder, A.J. Aranyosi, J.A. Rogers, R. Ghaffari, Sci. Adv. 6(50), eabe3929 (2020). https://doi.org/10.1126/sciadv.abe3929

    Article  Google Scholar 

  19. T.M. Fu, G.S. Hong, R.D. Viveros, T. Zhou, C.M. Lieber, Proc. Natl. Acad. Sci. U.S.A. 114, E10046 (2017)

    CAS  Google Scholar 

  20. I.R. Minev, P. Musienko, A. Hirsch, Q. Barraud, N. Wenger, E.M. Moraud, J. Gandar, M. Capogrosso, T. Milekovic, L. Asboth, R.F. Torres, N. Vachicouras, Q. Liu, N. Pavlova, S. Duis, A. Larmagnac, J. Voros, S. Micera, Z. Suo, G. Courtine, S.P. Lacour, Science 347, 159 (2015)

    CAS  Google Scholar 

  21. L.Z. Xu, S.R. Gutbrod, A.P. Bonifas, Y.W. Su, M.S. Sulkin, N.S. Lu, H.-J. Chung, K.-I. Jang, Z.J. Liu, M. Ying, C. Lu, R.C. Webb, J.-S. Kim, J.I. Laughner, H.Y. Cheng, Y.H. Liu, A. Ameen, J.-W. Jeong, G.-T. Kim, Y.G. Huang, I.R. Efimov, J.A. Rogers, Nat. Commun. 5, 3329 (2014)

    Google Scholar 

  22. C.-H. Chiang, S.M. Won, A.L. Orsborn, K.J. Yu, M. Trumpis, B. Bent, C. Wang, Y.G. Xue, S. Min, V. Woods, C.X. Yu, B.H. Kim, S.B. Kim, R. Huq, J.H. Li, K.J. Seo, F. Vitale, A. Richardson, H. Fang, Y.G. Huang, K. Shepard, B. Pesaran, J.A. Rogers, J. Viventi, Sci. Transl. Med. 12(538), eaay4682 (2020)

    Google Scholar 

  23. T.I. Kim, J.G. McCall, Y.H. Jung, X. Huang, E.R. Siuda, Y.H. Li, J.Z. Song, Y.M. Song, H.A. Pao, R.H. Kim, C.F. Lu, S.D. Lee, I.S. Song, G. Shin, R. Al-Hasani, S. Kim, M.P. Tan, Y.G. Huang, F.G. Omenetto, J.A. Rogers, M.R. Bruchas, Science 340, 211 (2013)

    CAS  Google Scholar 

  24. J.W. Jeong, J.G. McCall, G. Shin, Y.H. Zhang, R. Al-Hasani, M. Kim, S. Li, J.Y. Sim, K.I. Jang, Y. Shi, D.Y. Hong, Y.H. Liu, G.P. Schmitz, L. Xia, Z.B. He, P. Gamble, W.Z. Ray, Y.G. Huang, M.R. Bruchas, J.A. Rogers, Cell 162, 662 (2015)

    CAS  Google Scholar 

  25. Y.Y. Yang, M.Z. Wu, A. Vazquez-Guardado, A.J. Wegener, J.G. Grajales-Reyes, Y.J. Deng, T.Y. Wang, R. Avila, J.A. Moreno, S. Minkowicz, V. Dumrongprechachan, J. Lee, S.Y. Zhang, A.A. Legaria, Y.H. Ma, S. Mehta, D. Franklin, L. Hartmann, W.B. Bai, M.D. Han, H.B. Zhao, W. Lu, Y. Yu, X. Sheng, A. Banks, X.G. Yu, Z.R. Donaldson, R.W. Gereau, C.H. Good, Z.Q. Xie, Y.G. Huang, Y. Kozorovitskiy, J.A. Rogers, Nat. Neurosci. 24, 1035 (2021)

    CAS  Google Scholar 

  26. Y.X. Wu, M.Z. Wu, A. Vázquez-Guardado, J. Kim, X. Zhang, R. Avila, J.-T. Kim, Y.J. Deng, Y. Yu, S. Melzer, Y. Bai, H. Yoon, L.Z. Meng, Y. Zhang, H.X. Guo, L. Hong, E.E. Kanatzidis, C.R. Haney, E.A. Waters, A.R. Banks, Z.Y. Hu, F. Lie, L.P. Chamorro, B.L. Sabatini, Y.G. Huang, Y. Kozorovitskiy, J.A. Rogers, Nat. Commun. 13(1), 5571 (2022)

  27. S.I. Park, D.S. Brenner, G. Shin, C.D. Morgan, B.A. Copits, H.U. Chung, M.Y. Pullen, K.N. Noh, S. Davidson, S.J. Oh, J. Yoon, K.-I. Jang, V.K. Samineni, M. Norman, J.G. Grajales-Reyes, S.K. Vogt, S.S. Sundaram, K.M. Wilson, J.S. Ha, R.X. Xu, T.S. Pan, T.-I. Kim, Y.G. Huang, M.C. Montana, J.P. Golden, M.R. Bruchas, R.W. Gereau IV, J.A. Rogers, Nat. Biotechnol. 33, 1280 (2015)

    CAS  Google Scholar 

  28. A.D. Mickle, S.M. Won, K.N. Noh, J. Yoon, K.W. Meacham, Y.G. Xue, L.A. McIlvried, B.A. Copits, V.K. Samineni, K.E. Crawford, D.H. Kim, P. Srivastava, B.H. Kim, S. Min, Y. Shiuan, Y. Yun, M.A. Payne, J.P. Zhang, H. Jang, Y.H. Li, H.H. Lai, Y.G. Huang, S.I. Park, R.W. Gereau, J.A. Rogers, Nature 565, 361 (2019)

    CAS  Google Scholar 

  29. W. Ouyang, W. Lu, Y. Zhang, Y. Liu, J.U. Kim, H. Shen, Y. Wu, H. Luan, K. Kilner, S.P. Lee, Y. Lu, Y. Yang, J. Wang, Y. Yu, A.J. Wegener, J.A. Moreno, Z. Xie, Y. Wu, S.M. Won, K. Kwon, C. Wu, W. Bai, H. Guo, T.L. Liu, H. Bai, G. Monti, J. Zhu, S.R. Madhvapathy, J. Trueb, M. Stanslaski, E.M. Higbee-Dempsey, I. Stepien, N. Ghoreishi-Haack, C.R. Haney, T.I. Kim, Y. Huang, R. Ghaffari, A.R. Banks, T.C. Jhou, C.H. Good, J.A. Rogers, Nat. Biomed. Eng. (2023). https://doi.org/10.1038/s41551-023-01029-x

    Article  Google Scholar 

  30. S.W. Hwang, H. Tao, D.H. Kim, H.Y. Cheng, J.K. Song, E. Rill, M.A. Brenckle, B. Panilaitis, S.M. Won, Y.S. Kim, Y.M. Song, K.J. Yu, A. Ameen, R. Li, Y.W. Su, M.M. Yang, D.L. Kaplan, M.R. Zakin, M.J. Slepian, Y.G. Huang, F.G. Omenetto, J.A. Rogers, Science 337, 1640 (2012)

    CAS  Google Scholar 

  31. Y. Choi, J. Koo, J.A. Rogers, MRS Bull. 45(2), 103 (2020)

    Google Scholar 

  32. Q.S. Yang, Z.Y. Hu, M.-H. Seo, Y.M. Xu, Y. Yan, Y.-H. Hsu, J. Berkovich, K. Lee, T.-L. Liu, S. McDonald, H.L. Nie, H. Oh, M.Z. Wu, J.-T. Kim, S.A. Miller, Y. Jia, S. Butun, W.B. Bai, H.X. Guo, J. Choi, A. Banks, W.Z. Ray, Y. Kozorovitskiy, M.L. Becker, M.A. Pet, M.R. MacEwan, J.-K. Chang, H.L. Wang, Y.G. Huang, J.A. Rogers, Nat. Commun. 13, 6518 (2022). https://doi.org/10.1038/s41467-022-34173-0

    Article  Google Scholar 

  33. G. Lee, Y.S. Choi, H.J. Yoon, J.A. Rogers, Matter 3, 1031 (2020)

    Google Scholar 

  34. S.K. Kang, S.W. Hwang, H.Y. Cheng, S. Yu, B.H. Kim, J.H. Kim, Y.G. Huang, J.A. Rogers, Adv. Funct. Mater. 24, 4427 (2014)

    CAS  Google Scholar 

  35. J.H. Shin, Y. Yan, W.B. Bai, Y.G. Xue, P. Gamble, L.M. Tian, I. Kandela, C.R. Haney, W. Spees, Y. Lee, M. Choi, J. Ko, H. Ryu, J.K. Chang, M. Pezhouh, S.K. Kang, S.M. Won, K.J. Yu, J.N. Zhao, Y.K. Lee, M.R. MacEwan, S.K. Song, Y.G. Huang, W.Z. Ray, J.A. Rogers, Nat. Biomed. Eng. 3, 37 (2019)

    CAS  Google Scholar 

  36. K.J. Yu, D. Kuzum, S.W. Hwang, B.H. Kim, H. Juul, N.H. Kim, S.M. Won, K. Chiang, M. Trumpis, A.G. Richardson, H.Y. Cheng, H. Fang, M. Thompson, H. Bink, D. Talos, K.J. Seo, H.N. Lee, S.K. Kang, J.H. Kim, J.Y. Lee, Y.G. Huang, F.E. Jensen, M.A. Dichter, T.H. Lucas, J. Viventi, B. Litt, J.A. Rogers, Nat. Mater. 15, 782 (2016)

    CAS  Google Scholar 

  37. S.K. Kang, R.K.J. Murphy, S.W. Hwang, S.M. Lee, D.V. Harburg, N.A. Krueger, J.H. Shin, P. Gamble, H.Y. Cheng, S. Yu, Z.J. Liu, J.G. McCall, M. Stephen, H.Z. Ying, J. Kim, G. Park, R.C. Webb, C.H. Lee, S.J. Chung, D.S. Wie, A.D. Gujar, B. Vemulapalli, A.H. Kim, K.M. Lee, J.J. Cheng, Y.G. Huang, S.H. Lee, P.V. Braun, W.Z. Ray, J.A. Rogers, Nature 530, 71 (2016)

    CAS  Google Scholar 

  38. W.B. Bai, J. Shin, R.X. Fu, I. Kandela, D. Lu, X.Y. Ni, Y. Park, Z.H. Liu, T. Hang, D. Wu, Y.H. Liu, C.R. Haney, I. Stepien, Q.S. Yang, J. Zhao, K.R. Nandoliya, H. Zhang, X. Sheng, L. Yin, K. MacRenaris, A. Brikha, F. Aird, M. Pezhouh, J. Hornick, W.D. Zhou, J.A. Rogers, Nat. Biomed. Eng. 3, 644 (2019)

    Google Scholar 

  39. J.T. Reeder, Z.Q. Xie, Q.S. Yang, M.H. Seo, Y. Yan, Y.J. Deng, K.R. Jinkins, S.R. Krishnan, C. Liu, S. McKay, E. Patnaude, A. Johnson, Z.C. Zhao, M.J. Kim, Y.M. Xu, I. Huang, R. Avila, C. Felicelli, E. Ray, X. Guo, W.Z. Ray, Y.G. Huang, M.R. MacEwan, J.A. Rogers, Science 377, 109 (2022)

    CAS  Google Scholar 

  40. J. Koo, M.R. MacEwan, S.K. Kang, S.M. Won, M. Stephen, P. Gamble, Z.Q. Xie, Y. Yan, Y.Y. Chen, J. Shin, N. Birenbaum, S.J. Chung, S.B. Kim, J. Khalifeh, D.V. Harburg, K. Bean, M. Paskett, J. Kim, Z.S. Zohny, S.M. Lee, R.Y. Zhang, K.J. Luo, B.W. Ji, A. Banks, H.M. Lee, Y.G. Huang, W.Z. Ray, J.A. Rogers, Nat. Med. 24, 1830 (2018)

    CAS  Google Scholar 

  41. Y.S. Choi, R.T. Yin, A. Pfenniger, J. Koo, R. Avila, K.B. Lee, S.W. Chen, G. Lee, G. Li, Y. Qiao, A. Murillo-Berlioz, A. Kiss, S.L. Han, S.M. Lee, C.H. Li, Z.Q. Xie, Y.Y. Chen, A. Burrell, B. Geist, H. Jeong, J. Kim, H.J. Yoon, A. Banks, S.K. Kang, Z.J. Zhang, C.R. Haney, A.V. Sahakian, D. Johnson, T. Efimova, Y.G. Huang, G.D. Trachiotis, B.P. Knight, R.K. Arora, I.R. Efimov, J.A. Rogers, Nat. Biotechnol. 39, 1228 (2021)

    CAS  Google Scholar 

  42. Y. Zhang, F. Liu, Y. Zhang, J. Wang, D. D’Andrea, J.B. Walters, S. Li, H.J. Yoon, M. Wu, S. Li, Z. Hu, T. Wang, J. Choi, K. Bailey, E. Dempsey, K. Zhao, A. Lantsova, Y. Bouricha, I. Huang, H. Guo, X. Ni, Y. Wu, G. Lee, F. Jiang, Y. Huang, C.K. Franz, J.A. Rogers, Proc. Natl. Acad. Sci. U.S.A. 120(11), e2217734120 (2023)

    CAS  Google Scholar 

  43. I. Huang, Y.M. Zhang, H.M. Arafa, S.P. Li, A. Vazquez-Guardado, W. Ouyang, F. Liu, S. Madhvapathy, J.W. Song, A. Tzavelis, J. Trueb, Y. Choi, W.J. Jeang, V. Forsberg, E. Higbee-Dempsey, N. Ghoreishi-Haack, I. Stepien, K. Bailey, S.L. Han, Z.J. Zhang, C. Good, Y.G. Huang, A.J. Bandodkar, J.A. Rogers, Energy Environ. Sci. 15, 4095 (2022)

    CAS  Google Scholar 

  44. J.A. Rogers, MRS Bull. 44(3), 195 (2019)

    Google Scholar 

  45. Y.H. Zhang, Z. Yan, K.W. Nan, D.Q. Xiao, Y.H. Liu, H.W. Luan, H.R. Fu, X.Z. Wang, Q.L. Yang, J.C. Wang, W. Ren, H.Z. Si, F. Liu, L.H. Yang, H.J. Li, J.T. Wang, X.L. Guo, H.Y. Luo, L. Wang, Y.G. Huang, J.A. Rogers, Proc. Natl. Acad. Sci. U.S.A. 112, 11757 (2015)

    CAS  Google Scholar 

  46. Z. Yan, F. Zhang, F. Liu, M.D. Han, D.P. Ou, Y.H. Liu, Q. Lin, X.L. Guo, H.R. Fu, Z.Q. Xie, M.Y. Gao, Y.M. Huang, J. Kim, Y.T. Qiu, K.W. Nan, J. Kim, P. Gutruf, H.Y. Luo, A. Zhao, K.-C. Hwang, Y.G. Huang, Y.H. Zhang, J.A. Rogers, Sci. Adv. 2(9), e1601014 (2016). https://doi.org/10.1126/sciadv.1601014

    Article  Google Scholar 

  47. Y. Park, C.K. Franz, H. Ryu, H.W. Luan, K.Y. Cotton, J.U. Kim, T.S. Chung, S.W. Zhao, A. Vazquez-Guardado, D.S. Yang, K. Li, R. Avila, J.K. Phillips, M.J. Quezada, H. Jang, S.S. Kwak, S.M. Won, K. Kwon, H. Jeong, A.J. Bandodkar, M.D. Han, H.B. Zhao, G.R. Osher, H.L. Wang, K. Lee, Y.H. Zhang, Y.G. Huang, J.D. Finan, J.A. Rogers, Sci. Adv. 7(12), eabf9153 (2021). https://doi.org/10.1126/sciadv.abf9153

    Article  Google Scholar 

  48. H.W. Luan, Q.H. Zhang, T.-L. Liu, X.J. Wang, S.W. Zhao, H.L. Wang, S.L. Yao, Y.G. Xue, J.W. Kwak, W.B. Bai, Y.M. Xu, M.D. Han, K. Li, Z.W. Li, X.C. Ni, J.L. Ye, D.W. Choi, Q.S. Yang, J.-H. Kim, S. Li, S.L. Chen, C.S. Wu, D. Lu, J.-K. Chang, Z.Q. Xie, Y.G. Huang, J.A. Rogers, Sci. Adv. 7(43), eabj3686 (2021). https://doi.org/10.1126/sciadv.abj3686

    Article  Google Scholar 

  49. A. Kalra, A. Lowe, A.M. Al-Jumaily, J. Mater. Sci. Eng. 5(4), 100254 (2016)

    Google Scholar 

  50. S. Ramadan, N. Paul, H.E. Naguib, Biomed. Mater. 12, 025013 (2017)

    Google Scholar 

  51. Y. Ling, W.B. Pang, J.X. Liu, M. Page, Y.D. Xu, G.G. Zhao, D. Stalla, J.W. Xie, Y.H. Zhang, Z. Yan, Nat. Commun. 13, 524 (2022). https://doi.org/10.1038/s41467-022-28185-z

    Article  Google Scholar 

  52. G.C. Engelmayr, M.Y. Cheng, C.J. Bettinger, J.T. Borenstein, R. Langer, L.E. Freed, Nat. Mater. 7, 1003 (2008)

    CAS  Google Scholar 

  53. S. Budday, R. Nay, R. de Rooij, P. Steinmann, T. Wyrobek, T.C. Ovaert, E. Kuhl, J. Mech. Behav. Biomed. Mater. 46, 318 (2015)

    Google Scholar 

  54. T.R. Ray, J. Choi, A.J. Bandodkar, S. Krishnan, P. Gutruf, L.M. Tian, R. Ghaffari, J.A. Rogers, Chem. Rev. 119, 5461 (2019)

    CAS  Google Scholar 

  55. K.-I. Jang, K. Li, H.U. Chung, S. Xu, H.N. Jung, Y.Y. Yang, J.W. Kwak, H.H. Jung, J. Song, C. Yang, A. Wang, Z.J. Liu, J.Y. Lee, B.H. Kim, J.-H. Kim, J. Lee, Y. Yu, B.J. Kim, H. Jang, K.J. Yu, J. Kim, J.W. Lee, J.-W. Jeong, Y.M. Song, Y.G. Huang, Y.H. Zhang, J.A. Rogers, Nat. Commun. 8, 15894 (2017). https://doi.org/10.1038/ncomms15894

    Article  Google Scholar 

  56. D.H. Kim, J.H. Ahn, W.M. Choi, H.S. Kim, T.H. Kim, J.Z. Song, Y.G.Y. Huang, Z.J. Liu, C. Lu, J.A. Rogers, Science 320, 507 (2008)

    CAS  Google Scholar 

  57. D.H. Kim, J.Z. Song, W.M. Choi, H.S. Kim, R.H. Kim, Z.J. Liu, Y.Y. Huang, K.C. Hwang, Y.W. Zhang, J.A. Rogers, Proc. Natl. Acad. Sci. U.S.A. 105, 18675 (2008)

    CAS  Google Scholar 

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  1. Hedan Bai and Ziying Hu have contributed equally to this work.

Authors and Affiliations

  1. Querrey Simpson Institute for Bioelectronics, Northwestern University, Evanston, USA

    Hedan Bai, Ziying Hu & John A. Rogers

  2. Department of Materials Science and Engineering, Mechanical Engineering, Biomedical Engineering, Chemistry, Electrical Engineering and Computer Science, Dermatology, Northwestern University, Evanston, USA

    John A. Rogers

  3. Department of Neurological Surgery and Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, USA

    John A. Rogers

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  1. Hedan Bai
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Correspondence to John A. Rogers.

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J.A.R. is a co-founder of startup companies that are pursuing commercialization of certain technologies described in this article.

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Bai, H., Hu, Z. & Rogers, J.A. Hybrid materials approaches for bioelectronics. MRS Bulletin 48, 1125–1139 (2023). https://doi.org/10.1557/s43577-023-00620-6

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