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Bioinspired Artificial Protein Materials: Self-Assembly and Order from Nano to Macroscale

  • Multiscale Mechanics of Hierarchical Biological, Bioinspired, and Biomedical Materials
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Abstract

We describe the biosynthesis and characterization of protein materials comprised of two distinct self-assembling domains (SADs): elastin (E) found in tissue for its elastic properties and cartilage oligomeric matrix protein coiled-coil (COMPcc, C) predominantly locatedin joint and in bones. Based on earlier studies on protein block polymers comprised these two SADs, orientation and number of blocks play a crucial role in the overall stimuli-responsive supramolecular assembly behavior. Here we fabricate a range of EnC and CEn block polymers in which the E domain is systematically truncated to explore the effects of the E domain on the overall physicochemical behavior.

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Authors and Affiliations

  1. Polytechnic Institute of New York University, 6 Metrotech Center, Brooklyn, NY, 11201, USA

    Min Dai, Jennifer S. Haghpanah, Carlo Yuvienco & Jin Kim Montclare

  2. SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA

    Jin Kim Montclare

Authors
  1. Min Dai
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  2. Jennifer S. Haghpanah
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  3. Carlo Yuvienco
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  4. Jin Kim Montclare
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Dai, M., Haghpanah, J.S., Yuvienco, C. et al. Bioinspired Artificial Protein Materials: Self-Assembly and Order from Nano to Macroscale. MRS Online Proceedings Library 1301, 155–159 (2011). https://doi.org/10.1557/opl.2011.471

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  • DOI: https://doi.org/10.1557/opl.2011.471

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