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Quartz tuning fork as a mass sensitive biosensor platform with a bi-layer film modification via plasma polymerization

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Abstract

Due to the lack of the stability of amine films, a promising transducer, quartz-tuning fork (QTF) prongs were modified by a bi-layer film of plasma-polymerized n-heptane (hep) and then by ethylenediamine (EDA), respectively. For this purpose, the authors investigate the stability of amine-rich thin films both in air and aqueous medium. EDA films were deposited on QTF substrates by using an RF plasma system. The final amine-rich thin film was used to immobilize biologic recognition element. Model protein studies were showed that selected thin films could be adapted to QTF transducers to be used as a biosensor template.

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Authors and Affiliations

  1. Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Division, Graduate School of Science and Technology, TOBB University of Economics and Technology, Ankara, 06560, Turkey

    Hatice Ferda Özgüzar, Gizem Kaleli Can, Gözde Kabay, Mehmet Mutlu & Mehmet Mutlu

  2. Department of Biomedical Engineering, İzmir Democracy University, İzmir, 35140, Turkey

    Gizem Kaleli Can

Authors
  1. Hatice Ferda Özgüzar
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  2. Gizem Kaleli Can
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  3. Gözde Kabay
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  4. Mehmet Mutlu
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Corresponding author

Correspondence to Mehmet Mutlu.

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The supplementary material for this article can be found at https://doi.org/10.1557/mrc.2019.55

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Özgüzar, H.F., Can, G.K., Kabay, G. et al. Quartz tuning fork as a mass sensitive biosensor platform with a bi-layer film modification via plasma polymerization. MRS Communications 9, 710–718 (2019). https://doi.org/10.1557/mrc.2019.55

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