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The study of ultrasound-assisted extraction of flavonoids from Polygonum cuspidatum Sieb. et Zucc.

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  • Thermodynamics of Complex Solids
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Abstract

In this work, flavonoids in Polygonum cuspidatum Sieb. et Zucc. were extracted by ultrasound-assisted methodology and determined by ultraviolet–visible spectrophotometry. After that, extraction conditions were optimized by the single fact investigation, the central composite design, and response surface methodology (RSM) in turn. The results showed the optimal values of ethanol concentration, solid–liquid ratio, extraction temperature, extraction time, ultrasonic power, and number of extraction times were 60%, 1:20 (g/mL), 45 °C, 34 min; 80 W, and 5, respectively. The extraction ratio of flavonoids could be as high as 94.50%. The influence order of each factor was ultrasonic power > extraction time > extraction temperature > ethanol concentration. The results also showed that the experimental value was close to the predicted value (94.49%) of the established model by RSM, which proved that the established model was reasonable. The thermodynamic results showed that the extraction process was endothermic and could proceed spontaneously.

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Acknowledgment

This work was supported by the National Natural Science Foundation of China (Grant No. 51563015).

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Authors and Affiliations

  1. College of Materials Science and Engineering, Lanzhou University of Technology, Lanzhou, 730050, China

    Weiwei Jia, Zhenbin Chen, Yingyu Zhao & Ke Li

  2. State Key Laboratory of Gansu Advanced Non-ferrous Metal Materials, Lanzhou University of Technology, Lanzhou, 730050, China

    Weiwei Jia, Zhenbin Chen, Yingyu Zhao & Ke Li

  3. Department of Physics and Engineering, Frostburg State University, Frostburg, Maryland, 21532, USA

    Brandon Tichnell & Zhen Liu

  4. Guangzhou Key Laboratory for Surface Chemistry of Energy Materials, New Energy Research Institute, School of Environment and Energy, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou, 5100067, China

    Zhenghua Tang

  5. Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution Control, Guangdong Provincial Engineering and Technology Research Center for Environmental Risk Prevention and Emergency Disposal, School of Environment and Energy, South China University of Technology, Guangzhou Higher Education Mega Centre, Guangzhou, 510006, China

    Zhenghua Tang

  6. Soft Matter and Molecular Biophysics Group, Department of Applied Physics, University of Santiago de Compostela, Santiago de Compostela, 15782, Spain

    Juan M. Ruso

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  1. Weiwei Jia
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Correspondence to Zhenbin Chen or Zhen Liu.

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Jia, W., Chen, Z., Zhao, Y. et al. The study of ultrasound-assisted extraction of flavonoids from Polygonum cuspidatum Sieb. et Zucc.. Journal of Materials Research 34, 3254–3262 (2019). https://doi.org/10.1557/jmr.2019.144

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