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Recent developments in optofluidic-surface-enhanced Raman scattering systems: Design, assembly, and advantages

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Abstract

Surface-enhanced Raman scattering (SERS) coupled with micro- or nanofluidics integrated into optofluidic devices offer many advantages over conventional SERS conducted under static conditions. Higher reproducibility, larger intensity, as well as greater enhancement can be achieved by efficient mixing of analytes and SERS enhancers under a continuous flow. Progress and advances in the past 10 years, including the design of channels and efficient mixing conditions, assemblies of SERS substrates for optimal enhancement, and advantages of optofluidic-SERS analysis, are reviewed. Recent results show that optofluidic-SERS effectively overcomes many of the difficulties and limitations plaguing conventional SERS and the novel technique has enormous application potential.

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ACKNOWLEDGMENTS

This work was jointly supported by the National Natural Science Foundation of China under Grant No. 50801013, Natural Science Foundation of Jiangsu Province, China under Grant No. BK2009291, Specialized Research Fund for the Doctoral Program of Higher Education under Grant No. 200802861065, Excellent Young Teachers Program of Southeast University, Hong Kong Research Grants Council (RGC) General Research Fund (GRF) No. CityU 112307, and City University of Hong Kong Strategic Research Grant (SRG) No. 7008009.

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  1. Department of Physics, Southeast University, Nanjing, 211189, China

    Yin Yin & Teng Qiu

  2. Department of Physics and Materials Science, City University of Hong Kong, Kowloon, Hong Kong, China

    Wenjun Zhang & Paul K. Chu

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  1. Yin Yin
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Correspondence to Teng Qiu or Paul K. Chu.

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Yin, Y., Qiu, T., Zhang, W. et al. Recent developments in optofluidic-surface-enhanced Raman scattering systems: Design, assembly, and advantages. Journal of Materials Research 26, 170–185 (2011). https://doi.org/10.1557/jmr.2010.18

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  • DOI: https://doi.org/10.1557/jmr.2010.18

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