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Characterization of biofunctional thin films deposited by activated vapor silanization

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Abstract

A novel technique based in the combination of vapor silanization and chemical vapor deposition, hereafter referred to as activated vapor silanization (AVS), is shown to be an effective biofunctionalization technique. The AVS process results in thin organic films with a high surface amine concentration when deposited on substrates with different chemical characteristics, such as silicon, porous silicon, or gold. Chemical characterization shows that the films are composed of carbon (hydrocarbon, C–Si, C–C), silicon (different oxidation states), nitrogen (primary and secondary amines), oxygen, and hydrogen. Relevantly, the amines are also distributed along the film thickness, ensuring functionality even after some degradation of the films. AVS films behave practically as monocrystalline silicon substrates under loading–unloading tests. In addition, the AVS films behave as permeable membranes for molecules smaller than 5 Å, and the amine surface concentration is estimated to be 8 NH2/nm2 for molecules of about 12 Å, which is three times higher than that obtained with standard silanization procedures.

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Acknowledgments

The authors thank G. Hueso for his technical contributions. M. Arroyo-Hernández has been supported by a grant from the Education Ministry of Spain. Partial funding of this project has been provided by the CICyT (Contract No. TEC2004-05260-C02-01).

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Authors and Affiliations

  1. Faculty of Sciences, Department of Applied Physics C-12, Universidad Autónoma de Madrid, 28049, Cantoblanco, Madrid, Spain

    María Arroyo-Hernández & José M. Martínez-Duart

  2. Department of Materials Science, Escuela Técnica Superior de Ingenieros (ETSI) Caminos, Canales y Puertos, Universidad Politécnica de Madrid, 28040, Madrid, Spain

    José Pérez-Rigueiro

  3. Department of Corrosion and Protection, Centro Nacional de Investigaciones Metalúrgicas (CENIM-CSIC), 28040, Madrid, Spain

    Ana Conde

  4. Centro de Micro-Análisis de Materiales, Universidad Autónoma de Madrid, 28049, Madrid, Spain

    Aurelio Climent, Raul Gago & Miguel Manso

Authors
  1. María Arroyo-Hernández
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  2. José Pérez-Rigueiro
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  3. Ana Conde
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  4. Aurelio Climent
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  5. Raul Gago
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  6. Miguel Manso
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  7. José M. Martínez-Duart
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Correspondence to María Arroyo-Hernández.

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Arroyo-Hernández, M., Pérez-Rigueiro, J., Conde, A. et al. Characterization of biofunctional thin films deposited by activated vapor silanization. Journal of Materials Research 23, 1931–1939 (2008). https://doi.org/10.1557/JMR.2008.0241

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  • DOI: https://doi.org/10.1557/JMR.2008.0241

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