Abstract
Reduction of several polynitroarenes with isopropanol in a flow-type reactor in the presence of Al2O3 catalyst was studied. Temperature-controlled highly selective reduction of one, two, or three nitro groups in all the studied polynitroarenes proved to be feasible. N-alkylation of the reaction products was the predominant side reaction at high temperatures, except for the reduction of 2,7-dinitronaphthalene: in this case, a considerable amount of alkoxylated product was obtained. Benzo[c]cinnoline was the main product of reduction of 2,2′-dinitrobiphenyl.
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Sivcev, V.P., Volcho, K.P., Salakhutdinov, N.F. et al. Stepwise Selective Reduction of Polynitroarenes Using Isopropanol as a Source of Hydrogen in a Flow-Type Reactor in the Presence of Alumina. J Flow Chem 4, 113–117 (2014). https://doi.org/10.1556/JFC-D-14-00004
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DOI: https://doi.org/10.1556/JFC-D-14-00004