Journal of Flow Chemistry

, Volume 3, Issue 3, pp 103–107 | Cite as

Highlights from the Flow Chemistry Literature 2013 (Part 2)

Research Highlights


In this section of the journal, the continuous-flow chemistry literature of the preceding months is presented. Included are articles published in the period April–June 2013. Some key examples are highlighted in the form of graphical abstracts. The remaining publications in the field are then listed, ordered by journal name, with review articles grouped at the end.


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Further Flow Chemistry Publications

  1. “Peptide fragment coupling using a continuous-flow photochemical rearrangement of nitrones” Y. Zhang, M. L. Blackman, A. B. Leduc, T. F. Jamison Angewandte Chemie International Edition 2013, 52, 4251–4255.CrossRefGoogle Scholar
  2. “Chemotactic behavior of catalytic motors in microfluidic channels” L. Baraban, S. M. Harazim, S. Sanchez, O. G. Schmidt Angewandte Chemie International Edition 2013, 52, 5552–5556.CrossRefGoogle Scholar
  3. “Building a sulfonamide library by eco-friendly flow synthesis” A. Gioiello, E. Rosatelli, M. Teofrasti, P. Filipponi, R. Pellicciari ACS Combinatorial Science 2013, 15, 235–239.CrossRefGoogle Scholar
  4. “A simple millifluidic benchtop reactor system for the high-throughput synthesis and functionalization of gold nanoparticles with different sizes and shapes” S. E. Lohse, J. R. Eller, S. T. Sivapalan, M. R. Plews, C. J. Murphy ACS Nano 2013, 7, 4135–4150CrossRefGoogle Scholar
  5. “Continuous synthesis of device-grade semiconducting polymers in droplet-based microreactors” J. H. Bannock, S. H. Krishnadasan, A. M. Nightingale, C. Pang Yau, K. Khaw, D. Burkitt, J. J. M. Halls, M. Heeney, J. C. de Mello Advanced Functional Materials 2013, 23, 2123–2129.CrossRefGoogle Scholar
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  7. “Flock-based microfluidics” M. Hitzbleck, R. D. Lovchik, E. Delamarche Advanced Materials 2013, 25, 2672–2676.CrossRefGoogle Scholar
  8. “Iron-catalysed borylation of arenediazonium salts to give access to arylboron derivatives via aryl(amino)boranes at room temperature” L. D. Marciasini, N. Richy, M. Vaultier, M. Pucheaulta Advanced Synthesis and Catalysis 2013, 355, 1083–1088.CrossRefGoogle Scholar
  9. “3D-printed devices for continuous-flow organic chemistry” V. Dragone, V. Sans, M. H. Rosnes, P. J. Kitson, L. Cronin Beilstein Journal of Organic Chemistry 2013, 9, 951–959.CrossRefGoogle Scholar
  10. “Effects of fluid flow on the growth and assembly of ZnO nanocrystals in a continuous flow microreactor” C.-H. Choi, Y.-W. Su, C.-h. Chang CrystEngComm 2013, 15, 3326–3333.CrossRefGoogle Scholar
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  12. “Palladium-N-heterocyclic carbene (NHC) catalyzed C-N bond formation in a continuous flow microreactor. Effect of process parameters and comparison with batch operation” A. Pommella, G Tomaiuolo, A. Chartoire, S. Caserta, G Toscano, S. P. Nolan, S. Guido Chemical Engineering Journal 2013, 223, 578–583.CrossRefGoogle Scholar
  13. “Continuous flow synthesis of tungsten oxide (WO3) nanoplates from tungsten(VI) ethoxide” M. Gimeno-Fabra, P. Dunne, D. Grant, P. Gooden, E. Lester Chemical Engineering Journal 2013, 226, 22–29.CrossRefGoogle Scholar
  14. “A continuous-flow process for the synthesis of artemisinin” D. Kopetzki, F. Levesque, P. H. Seeberger Chemistry — A European Journal 2013, 19, 5450–5456.CrossRefGoogle Scholar
  15. “C-glycosyl amino acids through hydroboration-cross-coupling of exo-glycals and their application in automated solid-phase synthesis” S. Koch, D. Schollmeyer, H. Lö we, H. Kunz Chemistry — A European Journal 2013, 19, 7020–7041.CrossRefGoogle Scholar
  16. “Intramolecular [2+2] photocycloaddition of 3- and 4-(but-3-enyl)oxyquinolones: influence of the alkene substitution pattern, photophysical studies, and enantioselective catalysis by a chiral sensitizer” M. M. Maturi, M. Wenninger, R. Alonso, A. Bauer, A. Pöthig, E. Riedle, T. Bach Chemistry — A European Journal 2013, 19, 7461–7472.CrossRefGoogle Scholar
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  28. “Single-mode microwave reactor used for continuous flow reactions under elevated pressure” M. Nishioka, M. Miyakawa, Y Daino, H. Kataoka, H. Koda, K. Sato, T. M. Suzuki Industrial & Engineering Chemistry Research 2013, 52 4683–4687CrossRefGoogle Scholar
  29. “Preparation of barium sulfate nanoparticles in an interdigital channel configuration micromixer SIMM-V2” H. Wu, C. Wang, C. Zeng, L. Zhang Industrial & Engineering Chemistry Research 2013, 52, 5313–5320.CrossRefGoogle Scholar
  30. “The development of a capillary microreactor for transesterification reactions using lipase immobilized onto a silica monolith” S. T. Anuar, Y.-Y Zhao, S. M. Mugo, J. M. Curtis Journal of Molecular Catalysis B: Enzymatic 2013, 92, 62–70.CrossRefGoogle Scholar
  31. “Hydrazine-mediated reduction of nitro and azide functionalities catalyzed by highly active and reusable magnetic iron oxide nanocrystals” D. Cantillo, M. M. Moghaddam, C. O. Kappe Journal of Organic Chemistry 2013, 78, 4530–4542.CrossRefGoogle Scholar
  32. “Efficient [2+2] photocycloadditions under equimolar conditions by employing a continuous UV-flow reactor” M. Conradi, T. Junkers Journal of Photochemistry and Photobiology A: Chemistry 2013, 259, 41–46.CrossRefGoogle Scholar
  33. “Microwave dielectric heating of non-aqueous droplets in a microfluidic device for nanoparticle synthesis” D. Koziej, C. Floryan, R. A. Sperling, A. J. Ehrlicher, D. Issadore, R. Westervelt, D. A. Weitza Nanoscale 2013, 5, 5468–5475CrossRefGoogle Scholar
  34. “Ethyl acetate as an acyl donor in the continuous flow kinetic resolution of (±)-1-phenylethylamine catalyzed by lipases” A. S. de Miranda, L. S. M. Miranda, R. O. M. A. de Souza Organic & Biomolecular Chemistry 2013, 11, 3332–3336.CrossRefGoogle Scholar
  35. “Photocatalytic synthesis of allylic trifluoromethyl substituted styrene derivatives in batch and flow” L. M. Kreis, S. Krautwald, N. Pfeiffer, R. E. Martin, E. M. Carreira Organic Letters 2013, 15, 1634–1637.CrossRefGoogle Scholar
  36. “Pauson-Khand reactions in a photochemical flow microreactor” K. Asano, Y. Uesugi, J.-i. Yoshida Organic Letters 2013, 15, 2398–2401.CrossRefGoogle Scholar
  37. “Highly selective phosgene-free carbamoylation of aniline by dimethyl carbonate under continuous-flow conditions” S. Grego, F. Aricò, P. Tundo Organic Process Research and Development 2013, 17, 679–683.CrossRefGoogle Scholar
  38. “Mass transport and reactions in the tube-in-tube reactor” L. Yang, K. F. Jensen Organic Process Research and Development 2013, 17, 927–933.CrossRefGoogle Scholar
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  40. “Ozonolysis of some complex organic substrates in flow” M. D. Roydhouse, W. B. Motherwell, A. Constantinou, A. Gavriilidis, R. Wheeler, K. Down, I. Campbell RSC Advances 2012, 3, 5076–5082.CrossRefGoogle Scholar
  41. “Meso-scale microwave-assisted continuous flow reactions utilizing a selective heating matrix” M. J. Karney, K. A. Porter, E. K. Barnhardt, G. S. Vanier RSC Advances 2012, 3, 7106–7111.CrossRefGoogle Scholar
  42. “A supported aqueous phase catalyst coating in micro flow Mizoroki-Heck reaction” S. C. Stouten, Q. Wang, T. Noël, V. Hessel Tetrahedron Letters 2013, 54, 2194–2198.CrossRefGoogle Scholar
  43. “Efficient and scalable synthesis of ketones via nucleophilic Grignard addition to nitriles using continuous flow chemistry” C. Mateos, J. A. Rincón, J. Villanueva Tetrahedron Letters 2013, 54, 2226–2230.CrossRefGoogle Scholar
  44. “Continuous process for click reactions using glass micro-reactor functionalized with ß-cyclodextrin” M. N Tahir, R.-ul Qamar, A. Adnan, E. Cho, S. Jung, Tetrahedron Letters 2013, 54, 3268–3237.CrossRefGoogle Scholar
  45. “Synthesis of 12-membered macrocyclic templates and library analogs for PPI” J. Chen, F. Rong, B. Shan, Y. Chen, Y. Li, H. Yu, L. Chen, T. Kuang, S. Li, Y Chen, J. Du, C. Ai, J. Li, X. Li, C. Shi, Z.G. Jiang, Y. Long, Q. Gao, Z. Wang, K. Xu, X. Ran, H. Yi, D. Zhao, H. Qiao, J. Shen, B. Liu, C. Liu, K. Wu, X. Geng, J. Tan, D. McLeod, H. Frost, G Bai, G. Goetz, J. Federico III, C. Whitney-Pickett, M. Troutman, M. C. Noe, C. Guimaraes, D. W. Piotrowski, T. V. Magee Tetrahedron Letters 2013, 54, 3298–3301.CrossRefGoogle Scholar
  46. “Studies of a diastereoselective electrophilic fluorination reaction employing a cryo-flow reactor” K. Nakayama, D. L. Browne, I. R. Baxendale, S. V. Ley Synlett 2013, 24, 1298–1302.CrossRefGoogle Scholar


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  4. “Smart enzyme immobilization in microstructured reactors” J. M. Bolivar, B. Nidetzky Chemistry Today 2013, 31, 50–54.Google Scholar
  5. “Flow chemistry for designing sustainable chemical synthesis” B. R. Vaddula, M. A. Gonzalez Chemistry Today 2013, 31, 16–20.Google Scholar
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Copyright information

© Akadémiai Kiadó 2013

Authors and Affiliations

  1. 1.Institute of ChemistryKarl-Franzens-University GrazGrazAustria

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