Journal of Flow Chemistry

, Volume 3, Issue 2, pp 59–63 | Cite as

Highlights from the Flow Chemistry Literature 2013 (Part 1)

  • Toma N. Glasnov
Research Highlights


In this section of the journal, the continuous-flow chemistry literature of the preceding months is presented. Included are articles published in the period January–March 2013. Some key examples are highlighted in the form of graphical abstracts. The remaining publications in the field are then listed ordered by journal name, with review articles grouped at the end.


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Further Flow Chemistry Publications

  1. “Continuous Multistep Microfluidic Assisted Assembly of Fluorescent, Plasmonic, and Magnetic Nano structures” N. Hassan, V. Cabuil, A. Abou-Hassan Angewandte Chemie International Edition 2013, 52, 1994–1997CrossRefGoogle Scholar
  2. “Mild and Rapid Pd-Catalyzed Cross-Coupling with Hydrazine in Continuous Flow: Application to the Synthesis of Functionalized Heterocycles” A. DeAngelis, D.-H. Wang, S. L. Buchwald* Angewandte Chemie International Edition 2013, 52, 3434–3437CrossRefGoogle Scholar
  3. “Effect of Reaction Conditions on the Direct Synthesis of Hydrogen Peroxide with a AuPd/TiO2 Catalyst in a Flow Reactor” S. J. Freakley, M. Piccinini, J. K. Edwards, E. N. Ntainjua, J. A. Moulijn, G. J. Hutchings ACS Catalysis 2013, 3, 487–501CrossRefGoogle Scholar
  4. “Fabrication and Characterization of Stable Hydrophilic Microfluidic Devices Prepared via the in Situ Tertiary-Amine Catalyzed Michael Addition of Multifunctional Thiols to Multifunctional Acrylates” C. O. Bounds, J. Upadhyay, N. Totaro, S. Thakuri, L. Garber, M. Vincent, Z. Huang, M. Hupert, J. A. Pojman ACS Applied Materials & Interfaces 2013, 5, 1643–1655CrossRefGoogle Scholar
  5. “Continuous-Flow Asymmetrie Hydrogenation of the /3-Keto Ester Methyl Propionylacetate in Ionie Liquid-Supercritical Carbon Dioxide Biphasic Systems” J. Theuerkauf, G. Franci, W. Leitner Advanced Synthesis and Catalysis 2013, 355, 209–219CrossRefGoogle Scholar
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  10. “Flow Chemistry Synthèses of Styrenes, Unsymmetrical Stilbenes and Branched Aldehydes” S. L. Bourne, M. O’Brien, S. Kasinathan, P. Koos, P. Tolstoy, D. X. Hu, R. W. Bates, B. Martin, B. Schenkel, S. V. Ley* ChemCatChem 2013, 5, 159–172CrossRefGoogle Scholar
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  15. “Synthesis of Carbohydrate-Functionalised Sequence-Defmed 01igo(amidoamine)s by Photochemical Thiol-Ene Coupling in a Continuous Flow Reactor” F. Wojcik, A. G. O’Brien, S. Götze, P. H. Seeberger, L. Hartmann Chemistry — A European Journal 2013, 19, 3090–3098CrossRefGoogle Scholar
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  19. “Micro/Milliflow Processing with Selective Catalyst Microwave Heating in the Cu-Catalyzed Ullmann Etherification Reaction: A μ2-Process” F. Benaskar, N. G. Patii, E. V. Rebrov, A. Ben-Abdelmoumen, J. Meuldijk, L. A. Hulshof, V. Hessel, J. C. Schouten ChemSusChem 2013, 6, 353–366CrossRefGoogle Scholar
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  27. “Hydrodeoxygenation of 4-Propylguaiacol (2-Methoxy-4-propylphenol) in a Microreactor: Performance and Kinetic Studies” N. Joshi, A. Lawal Industriai & Engineering Chemistry Research 2013, 52, 4049–4058CrossRefGoogle Scholar
  28. “Continuous Precipitation of Ceria Nanoparticles from a Continuous Flow Micromixer” C. H. T. Tseng, B. K. Paul,* C.-H. Chang, M. H. Engelhard International Journal of Advanced Manufacturing Technology 2013, 64, 579–586CrossRefGoogle Scholar
  29. “Free Radical Polymerization of Butyl Acrylate in Monodispersed Droplets: Comparison Between Two Heating Strategies” L. Zhendong, L. Yangcheng, Y. Bodong, L. Guangsheng Journal of Applied Polymer Science 2013, 127, 628–635CrossRefGoogle Scholar
  30. “Large-Scale Synthesis of Nanocrystals in a Multichannel Droplet Reactor” A. M. Nightingale, J. H. Bannock, S. H. Krishnadasan, F. T. F. O’Mahony, S. A. Haque, J. Sloan, C. Drury, R. McIntyre, J. C. deMello* Journal of Materials Chemistry A 2013, 1, 4067–4076CrossRefGoogle Scholar
  31. “Continuous-Flow Preparation of Nanoporous Metal/Polymer Composite Particles by in situ Synthesis of Silver Nanoparticles in Photopolymerized Acrylate/Diethylene Glycol Droplets” J. M. Köhler, I. Kraus, J. Faerber, C. Serra Journal of Materials Science 2013, 48, 2158–2166CrossRefGoogle Scholar
  32. “Design and Synthesis of Diazatricyclodecane Agonists of the G-Protein-Coupled Receptor 119” E. Darout, R. P. Robinson, K. F. McClure,* M. Corbett, B. Li, A. Shavnya, M. P. Andrews, C. S. Jones, Q. Li, M. L. Minich, V. Mascitti, C. R. W. Guimarâes, M. J. Munchhof, K. B. Bahnck, C. Cai, D. A. Price, S. Liras, P. D. Bonin, P. Cornelius, R. Wang, V. Bagdasarian, C. P. Sobota, S. Hornby, V. M. Masterson, R. M. Joseph, A. S. Kalgutkar, Y. Chen Journal of Medicinal Chemistry 2013, 56, 301–319CrossRefGoogle Scholar
  33. “Ultrafast and Continuous Synthesis of Crystalline Ferrite Nanoparticles in Supercritical Ethanol” O. Pascu, S. Marre, C. Aymonier, A. Roig Nanoscale 2013, 5, 2126–2132CrossRefGoogle Scholar
  34. “Pulsed Supercritical Synthesis of Anatase TiO2 Nanoparticles in a Water-Isopropanol Mixture Studied by in situ Powder X-Ray Diffraction” J. R. Eltzholtz, C. Tyrsted, K. M. O. Jensen, M. Bremholm, M. Christensen, J. Becker-Christensen, B. B. Iversen Nanoscale 2013, 5, 2372–2378CrossRefGoogle Scholar
  35. “An Expeditious Synthesis of Imatinib and Analogues Utilizing Flow Chemistry Methods” M. D. Hopkin, I. R. Baxendale, S. V. Ley* Organic & Biomolecular Chemistry 2013, 11, 1822–1839CrossRefGoogle Scholar
  36. “Hydrogen-Free Alkene Reduction in Continuous Flow” A. S. Kleinke, T. F. Jamison Organic Letters 2013, 15, 710–713CrossRefGoogle Scholar
  37. “Green Diacetoxylation of Alkenes in a Microchemical System” J. H. Park, C. Y. Park, H. S. Song, Y. S. Huh, G. H. Kim, C. P. Park* Organic Letters 2013, 15, 752–755CrossRefGoogle Scholar
  38. “Scaffold Hopping via a Transannular Rearrangement-Encompassing Cascade” J. L. Vrijdag, A. M. Van den Bogaert, W. M. De Borggraeve Organic Letters 2013, 15, 1052–1055CrossRefGoogle Scholar
  39. “Generation and Reactions of Heteroaromatic Lithium Compounds by Using In-Line Mixer in a Continuous Flow Microreactor System at Mild Conditions” B. Liu, Y. Fan, X. Lv, X. Liu, Y. Yang, Y. Jia* Organic Process Research and Development 2013, 17, 133–137CrossRefGoogle Scholar
  40. “Continuous Flow Synthesis of n-Alkyl Chlorides in a High-Temperature Microreactor Environment” B. Reichart, G. Tekautz, C. O. Kappe Organic Process Research and Development 2013, 17, 152–157CrossRefGoogle Scholar
  41. “On the Fischer Indole Synthesis of 7-Ethyltryptophol — Mechanistic and Process Intensification Studies under Continuous Flow Conditions” B. Gutmann, M. Gottsponer, P. Elsner, D. Cantillo, D. M. Roberge, C. O. Kappe Organic Process Research and Development 2013, 17, 294–302CrossRefGoogle Scholar
  42. “A High-Output, Continuous Selective and Heterogeneous Nitration of p-Difluorobenzene” Z. Yu, Y. Lv, C. Yu,* W. Su Organic Process Research and Development 2013, 17, 438–442CrossRefGoogle Scholar
  43. “Thinking Continuously: A Microreactor for the Production and Scale-Up of Biodegradable, Self-Assembled Nanoparticles” C. Petschacher, A. Eitzlmayr, M. Besenhard, J. Wagner, J. Barthelmes, A. Bernkop-Schnürch, J. G. Khinast, A. Zimmer Polymer Chemistry 2013, 4, 2342–2352CrossRefGoogle Scholar
  44. “Expedient Method for Samarium(II) Iodide Preparation Utilizing a Flow Approach” S. Voltrova, J. Srogl Synlett 2013, 24, 394–396Google Scholar


  1. “Functionalized Magnetizable Particles for Downstream Processing in Single-Use Systems” N. Tippkötter, H. Al-Kaidy, S. Wollny, R. Ulber* Chemie Ingenieur Technik 2013, 85, 76–86CrossRefGoogle Scholar
  2. “Microfluidic Device: A Miniaturized Platform for Chemical Reactions” Q. Tu, L. Pang, Y. Zhang, M. Yuan, J. Wang, D. Wang, W. Liu, J. Wang* Chinese Journal of Chemistry 2013, 31, 304–316CrossRefGoogle Scholar
  3. “Flow Photochemistry: Old Light through New Windows” J. P. Knowles, L. D. Elliott, K. I. Booker-Milburn* Beilstein Journal of Organic Chemistry 2012, 8, 2025–2052CrossRefGoogle Scholar
  4. “Highlights of Photochemical Reactions in Microflow Reactors” M. Oelgemöller Chemical Engineering & Technology 2012, 35, 1144–1152CrossRefGoogle Scholar
  5. “Membrane Microreactors: Gas-Liquid Reactions Made Easy” T. Nöel,* V. Hessel ChemSusChem 2013, 6, 405–407CrossRefGoogle Scholar
  6. “The Integration of Flow Reactors into Synthetic Organic Chemistry” Ian R. Baxendales Journal of Chemical Technology and Biotechnology 2013, 88, 519–552CrossRefGoogle Scholar

Copyright information

© Akadémiai Kiadó 2013

Authors and Affiliations

  1. 1.Institute of ChemistryKarl-Franzens-University GrazGrazAustria

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