Journal of Flow Chemistry

, Volume 2, Issue 2, pp 37–42 | Cite as

Positron Emission Tomography Radiosynthesis in Microreactors

  • Paul Watts
  • Giancarlo Pascali
  • Piero A. Salvadori


Positron emission tomography (PET) is a very powerful diagnostic technique routinely used in a variety of medical applications. This review article summarises the developments of using microreactor technology for the radiochemical synthesis of PET agents. The advantages of manufacturing these imaging drugs using microreactors are described, and a review of reactions conducted to date is outlined.


microreactor continuous flow synthesis positron emission tomography PET radiochemistry 11C and 18F isotopes 


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Copyright information

© Akadémiai Kiadó 2012

Authors and Affiliations

  • Paul Watts
    • 1
  • Giancarlo Pascali
    • 2
  • Piero A. Salvadori
    • 2
  1. 1.Department of ChemistryUniversity of HullHullUK
  2. 2.CNR Institute of Clinical PhysiologyPisaItaly

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