Abstract
We investigated the effect of homogeneous and inhomogeneous static magnetic field (SMF) exposure on the thermal nociceptive threshold of snail in the hot plate test (43 °C). Both homogeneous (hSMF) and inhomogeneous (iSMF) SMF increased the thermo-nociceptive threshold: 40.2%, 29.2%, or 41.7% after an exposure of 20, 30, or 40 min hSMF by p<0.001, p<0.0001, or p<0.001, and 32.7% or 46.2% after an exposure of 20 or 40 min iSMF by p<0.05 or p<0.0001. These results suggest that SMF has an antinociceptive effect in snail. On the other hand, naloxone as an atypical opioid antagonist in an amount of 1 μg/g was found to significantly decrease the thermo-nociceptive threshold (41.9% by p<0.002), which could be antagonized by hSMF exposure implying that hSMF exerts its antinociceptive effect partly via opioid receptors.
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Acknowledgment
The authors are grateful to Prof. Zs. Fürst and Dr. M. Al-Khrasani for their kind contribution to the measurements.
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László, J.F., Hernádi, L. Whole Body Static Magnetic Field Exposure Increases Thermal Nociceptive Threshold in the Snail, helix Pomatia. BIOLOGIA FUTURA 63, 441–452 (2012). https://doi.org/10.1556/ABiol.63.2012.4.3
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DOI: https://doi.org/10.1556/ABiol.63.2012.4.3