To detect neuroactive factors in biological fluids, we have previously elaborated a moveable biosensor, the preparation of isolated neuron penetrated with recording microelectrode . Here, we report that, in the pond snail, signals emanated from a central pattern generator (CPG) for feeding and detected by such biosensor correspond to long-term changes in motor output of the CPG as recorded from buccal nerves. The results suggest that combined recording from motor nerves, neurons in situ and the neuron-based biosensors may be a useful tool in studies of the mechanisms underlying network organisation.
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Initiation of feeding cycles by a single buccal interneurone. J. Exp. Biol. 92, 187–201.
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Chistopolsky, I.A., Vorontsov, D.D. & Sakharov, D.A. Monitoring of Neuroactive Factors Released from a Pattern-Generating Network. BIOLOGIA FUTURA 59, 29–31 (2008). https://doi.org/10.1556/ABiol.59.2008.Suppl.4
- central pattern generator
- extrasynaptic space
- isolated neuron
- Lymnaea stagnalis