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Monitoring of Neuroactive Factors Released from a Pattern-Generating Network

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Abstract

To detect neuroactive factors in biological fluids, we have previously elaborated a moveable biosensor, the preparation of isolated neuron penetrated with recording microelectrode [1]. Here, we report that, in the pond snail, signals emanated from a central pattern generator (CPG) for feeding and detected by such biosensor correspond to long-term changes in motor output of the CPG as recorded from buccal nerves. The results suggest that combined recording from motor nerves, neurons in situ and the neuron-based biosensors may be a useful tool in studies of the mechanisms underlying network organisation.

References

  1. 1.

    Chistopolsky, I. A., Sakharov, D. A. (2007) An isolated neuron-based biosensor to release of neuroactive substances. Russ. J. Physiol. 93, 1210–1213 (in Russian).

    Google Scholar 

  2. 2.

    Dyakonova, T. L. (1985) Two types of neurons which differ in plasticity: study of ionic mechanisms. Zhurn. Vyssh. Nerv. Deyat. 35, 552–560 (in Russian).

    Google Scholar 

  3. 3.

    Rose, R. M., Benjamin, P. R. (1981) Interneuronal control of feeding in the pond snail Lymnaea stagnalis.

    Google Scholar 

  4. 1.

    Initiation of feeding cycles by a single buccal interneurone. J. Exp. Biol. 92, 187–201.

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Correspondence to I. A. Chistopolsky.

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Chistopolsky, I.A., Vorontsov, D.D. & Sakharov, D.A. Monitoring of Neuroactive Factors Released from a Pattern-Generating Network. BIOLOGIA FUTURA 59, 29–31 (2008). https://doi.org/10.1556/ABiol.59.2008.Suppl.4

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Keywords

  • Neuroethology
  • central pattern generator
  • extrasynaptic space
  • isolated neuron
  • Lymnaea stagnalis