Abstract
In the pond snail Lymnaea stagnalis, D-glucose action was investigated on electrical activity of identified central neurons.
In the CNS preparations isolated from specimens that starved for 24–96 h., D-glucose added to a. standard or HiDi saline at 500–700 μg/ml effectively hyperpolarized ca. 90% of feeding related neurons Bl, SO and CGC. However, not all feeding-related neurons examined were responsive to glucose.
Experiments on cells of the serotonergic Pedal A. cluster have shown that hyperpolarizing action of D-glucose is retained following complete isolation of „hunger” neurons. Threshold concentration producing 1–3 mV hyperpolarization was ca. 50 μg/ml.
The results suggest a. direct glucose involvement in the mechanisms that control feeding behavior in Lymnaea.
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Presented at the 10th ISIN Symposium on Invertebrate Neurobiology, July 1–5, 2003, Tihany, Hungary.
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Alania, M., Dyakonova, V. & Sakharov, D.A. Hyperpolarization by Glucose of Feeding-Related Neurons in Snail. BIOLOGIA FUTURA 55, 195–200 (2004). https://doi.org/10.1556/ABiol.55.2004.1-4.24
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DOI: https://doi.org/10.1556/ABiol.55.2004.1-4.24