Advertisement

Acta Biologica Hungarica

, Volume 63, Supplement 2, pp 217–220 | Cite as

Serotonin Transport and Synthesis Systems During Early Development of Invertebrates: Functional Analysis on a Bivalve Model

Short Communication
  • E. G. IvashkinEmail author
  • Marina Yu. Khabarova
  • Elena E. Voronezhskaya
Article

Abstract

Serotonin (5.HT) is known to be functionally active during early development in both vertebrates and invertebrates. However, the presence of 5-HT and its synthesis and transport system has not yet been demonstrated in bivalve early development. The presence of 5-HT was immunochemically demonstrated at the cleavage stage of bivalve Mytilus trossulus. 5-HT level dramatically increased within all embryonic cells after incubation with 5-HTP but not after incubation with tryptophan and 5-HT. The first 5-HT uptake by specific transporter was detected at 13 hpf blastula stage only and it was restricted to one distinct cell.

Keywords

Serotonin SERT Mytilus trossulus Mollusca cleavage blastula 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Amireault, P., Dubé, F. (2005) Serotonin and its antidepressant-sensitive transport in mouse cumulusoocyte complexes and early embryos. Biol. Reprod. 73, 358–365.CrossRefGoogle Scholar
  2. 2.
    Azmitia, E. C. (2001) Modern views on an ancient chemical: serotonin effects on cell proliferation, maturation, and apoptosis. Brain Res. Bull. 56, 413–424.CrossRefGoogle Scholar
  3. 3.
    Buznikov, G. A., Lambert, H. W., Lauder, J. M. (2001) Serotonin and serotonin-like substances as regulators of early embryogenesis and morphogenesis. Cell Tissue Res. 305, 177–186.CrossRefGoogle Scholar
  4. 4.
    Buznikov, G. A. (2007) Preneural transmitters as regulators of embryogenesis. Current state of the problem. Russ. J. Dev. Biol. 38, 213–220.CrossRefGoogle Scholar
  5. 5.
    Berger, M., Gray, J. A., Roth, B. L. (2009) The expanded biology of serotonin. Annu. Rev. Med. 60, 355–366.CrossRefGoogle Scholar
  6. 6.
    Caveney, S., Cladman, W., Verellen, L. A., Donly, C. (2006) Ancestry of neuronal monoamine transporters in the Metazoa. J. Exp. Biol. 209, 4858–4868.CrossRefGoogle Scholar
  7. 7.
    Fukumoto, T., Blakely, R. D., Levin, M. (2005) Serotonin transporter function is a novel element of left-right patterning. J. Dev. Neurosci. 27, 349–363.CrossRefGoogle Scholar
  8. 8.
    Voronezhskaya, E. E., Nezlin, L. P., Odintsova, N. A., Plummer, J. T., Croll, R. P. (2008) Neuronal development in larval mussel Mytilus trossulus (Mollusca: Bivalvia). Zoomorphology 127, 97–110.CrossRefGoogle Scholar

Copyright information

© Akadémiai Kiadó, Budapest 2012

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • E. G. Ivashkin
    • 1
    Email author
  • Marina Yu. Khabarova
    • 1
  • Elena E. Voronezhskaya
    • 1
  1. 1.Department of Comparative PhysiologyInstitute of Developmental Biology RASMoscowRussia

Personalised recommendations