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Acta Biologica Hungarica

, Volume 63, Supplement 2, pp 206–209 | Cite as

Pharmacological Analysis of Locomotion and Heart Contraction During the Development of Helisoma (Mollusca: Gastropoda)

Short Communication
  • Marina Yu. Khabarova
  • Elena E. VoronezhskayaEmail author
Open Access
Article

Abstract

We investigated involvement of different 5-HT receptors in regulation of ciliary rotation, gliding locomotion and heartbeat of Helisoma embryo at pre- and post-metamorphic stages. Pharmacological analysis suggested that activation of 5-HT1 receptor enhance ciliary rotation but do not affect gliding locomotion. Activation of 5-HT4 receptor depresses both types of locomotion. Before metamorphosis heart contraction is depressed by activation of 5-HT4 and enhanced by activation of 5-HT7 receptor. However, the heart became insensitive to all agonists by hatching. We hypothesized that alterations in affinity or expression of particular 5-HT receptors can underlie the well-coordinated character of serotonin-dependent larval behavior.

Keywords

5-HT agonists ciliary rotation gliding locomotion heartbeat 

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Copyright information

© Akadémiai Kiadó, Budapest 2012

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Marina Yu. Khabarova
    • 1
  • Elena E. Voronezhskaya
    • 1
    Email author
  1. 1.Department of Comparative PhysiologyInstitute of Developmental Biology RASMoscowRussia

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