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Acta Biologica Hungarica

, Volume 59, Supplement 2, pp 39–46 | Cite as

Humoral Serotonin and Dopamine Modulate the Feeding in The Snail, Helix pomatia

  • L. HernádiEmail author
  • L. Kárpáti
  • J. Győri
  • Ágnes Vehovszky
  • L. Hiripi
Article

Abstract

We investigated the effect of elevated levels of humoral 5HT and DA on the feeding latency of Helix pomatia, 1 day, 3 days and 10 days following satiation, by injecting monoamines into the haemocoel. HPLC assay of monoamines showed that both 5HT and DA are present in pmol/ml concentrations in the haemolymph of both starved and non-starved animals. Elevated levels of 5HT and DA were most effective at decreasing the feeding latency 10 days following satiation when DA decreased the feeding latency in a concentration dependent manner between 10−7 and 10−5 M whereas 5HT levels decreased the feeding latency only at 10−6 M but increased it at 10−5 M. Immunocytochemistry revealed that both 5HT3 and D1 receptor-like immuno-reactivity are present in cell bodies located in the same areas of the buccal ganglia. Our observations suggest that both humoral DA and 5HT mutually modulate the activity of the feeding CPG through neurons which have these receptors.

Keywords

Arousal D1 receptor-motivation 5HT3 receptor feeding latency 

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Copyright information

© Akadémiai Kiadó, Budapest 2008

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • L. Hernádi
    • 1
    Email author
  • L. Kárpáti
    • 2
  • J. Győri
    • 1
  • Ágnes Vehovszky
    • 1
  • L. Hiripi
    • 1
  1. 1.Department of Experimental Zoology, Balaton Limnological Research InstituteHungarian Academy of SciencesTihanyHungary
  2. 2.Department of Clinical Biochemistry and Molecular Pathology, Medical and Health Science CenterUniversity of DebrecenDebrecenHungary

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