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Acta Biologica Hungarica

, Volume 59, Supplement 2, pp 29–31 | Cite as

Monitoring of Neuroactive Factors Released from a Pattern-Generating Network

Short Communication
  • I. A. ChistopolskyEmail author
  • D. D. Vorontsov
  • D. A. Sakharov
Article

Abstract

To detect neuroactive factors in biological fluids, we have previously elaborated a moveable biosensor, the preparation of isolated neuron penetrated with recording microelectrode [1]. Here, we report that, in the pond snail, signals emanated from a central pattern generator (CPG) for feeding and detected by such biosensor correspond to long-term changes in motor output of the CPG as recorded from buccal nerves. The results suggest that combined recording from motor nerves, neurons in situ and the neuron-based biosensors may be a useful tool in studies of the mechanisms underlying network organisation.

Keywords

Neuroethology central pattern generator extrasynaptic space isolated neuron Lymnaea stagnalis 

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References

  1. 1.
    Chistopolsky, I. A., Sakharov, D. A. (2007) An isolated neuron-based biosensor to release of neuroactive substances. Russ. J. Physiol. 93, 1210–1213 (in Russian).Google Scholar
  2. 2.
    Dyakonova, T. L. (1985) Two types of neurons which differ in plasticity: study of ionic mechanisms. Zhurn. Vyssh. Nerv. Deyat. 35, 552–560 (in Russian).Google Scholar
  3. 3.
    Rose, R. M., Benjamin, P. R. (1981) Interneuronal control of feeding in the pond snail Lymnaea stagnalis.Google Scholar
  4. 1.
    Initiation of feeding cycles by a single buccal interneurone. J. Exp. Biol. 92, 187–201.Google Scholar

Copyright information

© Akadémiai Kiadó, Budapest 2008

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • I. A. Chistopolsky
    • 1
    Email author
  • D. D. Vorontsov
    • 1
  • D. A. Sakharov
    • 1
  1. 1.Laboratory of Comparative Physiology, Institute of Developmental BiologyRussian Academy of SciencesMoscowRussia

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