Acta Biologica Hungarica

, Volume 59, Supplement 2, pp 117–122 | Cite as

Adult-to-Embryo Chemical Signaling in the Regulation of Larval Development in Trochophore Animals: Cellular and Molecular Mechanisms

  • Elena E. VoronezhskayaEmail author
  • K. I. Glebov
  • Marina Yu. Khabarova
  • E. G. Ponimaskin
  • L. P. Nezlin


The regulation of larval development by starved adults occurs in both freshwater snails, Helisoma trivolvis and marine polychaetes, Platynereis dumerilii. Serotonin (5-HT) links this environmental signal which is detected by larval apical sensory neurons to changes in larval development. A profile of the stage-dependent expression of 5-HT receptors and coupled G proteins is essential in this regulatory mechanism. The final effect on development depends on the modulation of the activity of the larval digestive system.


Serotonin receptors chemical signaling larval developmental regulation Trochozoa 


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© Akadémiai Kiadó, Budapest 2008

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Elena E. Voronezhskaya
    • 1
    Email author
  • K. I. Glebov
    • 2
  • Marina Yu. Khabarova
    • 3
  • E. G. Ponimaskin
    • 2
  • L. P. Nezlin
    • 1
  1. 1.Department of Comparative PhysiologyInstitute for Developmental BiologyMoscowRussia
  2. 2.Department of Neuro- and Sensory PhysiologyUniversity of GöttingenGöttingenGermany
  3. 3.Department of Human and Animal Morphology and PhysiologyTula State Pedagogical UniversityTulaRussia

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