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Acta Biologica Hungarica

, Volume 59, Issue 3, pp 357–363 | Cite as

The Glutathione Response to Salt Stress in the Thermophilic Fungus, Thermomyces Lanuginosus

  • Helene Friborg Jepsen
  • I. Pocsi
  • B. JensenEmail author
Open Access
Article

Abstract

In order to investigate the role of glutathione in response to salt stress in the thermophilic fungus. Thermomyces lanuginosus, the biomass and the intracellular pool of protein and the glutathione + glutathione disulphid (GSH + GSSG) was measured for four days in a medium with NaCl or KCl added and in the basal medium. Due to the osmotic and ionic stress imposed by the salts, the growth o. T. lanuginosus was delayed and the inhibitory effect of KCl exceeded that of NaCl. Glutathione seemed to be involved in the response o. T. lanuginosus towards high concentrations of salt, as the level of stress was negatively correlated with the amount of total glutathione. Salt stress did not result in an increased intracellular protein production. GSH accumulated while nutrients were abundant and were subsequently degraded later, suggesting that nutrients stored in GSH are used when the medium is depleted.

Keywords

Ionic stress osmotic stress growth protein concentration GSH 

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© Akadémiai Kiadó, Budapest 2008

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  1. 1.Department of MicrobiologyUniversity of CopenhagenCopenhagen KDenmark
  2. 2.Department of Microbial Biotechnology and Cell BiologyUniversity of DebrecenDebrecenHungary

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