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Acta Biologica Hungarica

, Volume 58, Supplement 1, pp 95–111 | Cite as

Definition of Drosophila Hemocyte Subsets by Cell-Type Specific Antigens

  • Éva Kurucz
  • B. Váczi
  • R. Márkus
  • Barbara Laurinyecz
  • P. Vilmos
  • J. Zsámboki
  • Kinga Csorba
  • Elisabeth Gateff
  • D. Hultmark
  • I. AndóEmail author
Article

Abstract

We analyzed the heterogeneity of Drosophila hemocytes on the basis of the expression of cell-type specific antigens. The antigens characterize distinct subsets which partially overlap with those defined by morphological criteria. On the basis of the expression or the lack of expression of blood cell antigens the following hemocyte populations have been defined: crystal cells, plasmatocytes, lamellocytes and precursor cells. The expression of the antigens and thus the different cell types are developmentally regulated. The hemocytes are arranged in four main compartments: the circulating blood cells, the sessile tissue, the lymph glands and the posterior hematopoietic tissue. Each hemocyte compartment has a specific and characteristic composition of the various cell types. The described markers represent the first successful attempt to define hemocyte lineages by immunological markers in Drosophila and help to define morphologically, functionally, spatially and developmentally distinct subsets of hemocytes.

Keywords

Drosophila hemocyte antigen hemocyte subpopulation monoclonal antibody hemocyte development 

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© Akadémiai Kiadó, Budapest 2007

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Éva Kurucz
    • 1
  • B. Váczi
    • 1
  • R. Márkus
    • 1
  • Barbara Laurinyecz
    • 1
  • P. Vilmos
    • 1
  • J. Zsámboki
    • 1
  • Kinga Csorba
    • 1
  • Elisabeth Gateff
    • 2
  • D. Hultmark
    • 3
  • I. Andó
    • 1
    Email author
  1. 1.Biological Research Center of the Hungarian Academy of SciencesSzegedHungary
  2. 2.Institut für GenetikJohannes Gutenberg Universität MainzMainzGermany
  3. 3.Umea Center for Molecular PathologyUmea UniversityUmeaSweden

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