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Acta Biologica Hungarica

, Volume 58, Issue 3, pp 269–279 | Cite as

Investigation of Lipid Peroxide and Glutathione Redox Status of Chicken Conserning on High Dietary Selenium Intake

  • K. BaloghEmail author
  • Mária Weber
  • Márta Erdélyi
  • M. Mézes
Article
  • 5 Downloads

Abstract

This study was designed to investigate the effects of excess (24.5 mg Se/kg feed) inorganic and organic dietary selenium supplementation on 3-week-old broilers. The experiments lasted 4 days. Intensity of lipid peroxidation processes (malondialdehyde, MDA) and the amount (reduced glutathione, GSH) and activity (glutathione peroxidase activity, GSHPx) of gluathione redox system were measured in blood plasma, red blood cell hemolysate and liver. Voluntary feed intake in the selenium-treated groups reduced remarkably. Elevated GSH concentration and GSHPx activity were measured in plasma and liver of both selenium-treated groups compared to the untreated control and the ‘pair-fed’ controls. The lipid peroxidation processes in the liver showed higher intensity than the control due to both selenium treatment. The applied dose of selenite and selenomethionine does not inhibit, but even improves the activity of glutathione redox system in the liver during the early period of selenium exposure.

Keywords

Chicken sodium-selenite selenomethionine glutathione redox system lipid peroxidation 

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© Akadémiai Kiadó, Budapest 2007

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • K. Balogh
    • 1
    Email author
  • Mária Weber
    • 1
  • Márta Erdélyi
    • 1
  • M. Mézes
    • 1
  1. 1.Department of Nutrition, Faculty of Agricultural and Environmental SciencesSzent István UniversityGödöllőHungary

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