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Acta Biologica Hungarica

, Volume 55, Issue 1–4, pp 177–183 | Cite as

Second Messengers of Octopamine Receptors in the Snail Lymnaea

  • Samantha Pitt
  • Ágnes Vehovszky
  • Henriette Szabó
  • C. J. H. ElliottEmail author
Article

Abstract

We describe octopamine responses of 3 large buccal neurons of Lymnaea and test the hypothesis that these are cAMP-dependent.

The B1 neuron is excited by octopamine and the depolarisation is significantly enlarged (P < 0.05) by application of the blocker of cAMP breakdown, 3-isobutyl-l-methylxanthine (IBMX). The Bl neuron is also depolarised by forskolin, an activator of adenylyl cyclase.

The B2 and B3 neurons are inhibited by octopamine, and the response is not affected by IBMX. Both cells are excited by forskolin.

We conclude that the Bl neuron response to octopamine is likely to be mediated by cAMP, while the B2 and B3 responses are cAMP-independent.

Keywords

Lymnaea stagnalis feeding octopamine receptor second messenger 

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© Akadémiai Kiadó, Budapest 2004

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Authors and Affiliations

  • Samantha Pitt
    • 1
    • 3
  • Ágnes Vehovszky
    • 1
    • 2
  • Henriette Szabó
    • 2
  • C. J. H. Elliott
    • 1
    Email author
  1. 1.Department of BiologyUniversity of YorkYorkEngland
  2. 2.Department of Experimental Zoology, Balaton Limnological Research InstituteHungarian Academy of SciencesTihanyHungary
  3. 3.Department of PhysiologyUniversity of CambridgeCambridgeEngland

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